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无处不在的不动杆菌属物种作为有益共生菌,但逐渐被抗生素耐药基因所助长。

Ubiquitous Acinetobacter species as beneficial commensals but gradually being emboldened with antibiotic resistance genes.

机构信息

Applied and Environmental Microbiology Research Group AEMREG, Department of Biochemistry and Microbiology, University of Fort Hare, Alice, South Africa.

出版信息

J Basic Microbiol. 2012 Dec;52(6):620-7. doi: 10.1002/jobm.201100323. Epub 2012 Feb 23.

Abstract

Acinetobacter spp. are ubiquitous obligate aerobic bacteria which occur mostly as commensals on the skin, and in soil, water and plants' rhizosphere. Though the species in this genus have been implicated as aetiologies in some nosocomial infections, their versatility covers biodegradation or dissolution leading to bioremediation; catalysis leading to synthesis of high molecular weight, life sustaining polymers; and as growth enhancers in agriculture. The challenge of antibiotic resistance and their mediatory genes is a cause for concern but should not deter the beneficial application of the bacteria especially in the synthesis of novel compounds that would be of relevance in overcoming some global ecological challenges. This review addresses important beneficial attributes of Acinetobacter species as well as gives some insight into emerging trends in their resistance to antibiotics.

摘要

不动杆菌属是普遍存在的需氧细菌,主要作为皮肤和土壤、水和植物根际的共生菌存在。虽然该属的一些物种已被认为是某些医院感染的病因,但它们的多功能性涵盖了生物降解或溶解导致的生物修复;催化导致高分子量、维持生命的聚合物的合成;以及在农业中作为生长促进剂。抗生素耐药性及其介导基因的挑战令人担忧,但不应阻止细菌的有益应用,特别是在合成新型化合物方面,这将有助于克服一些全球生态挑战。本综述介绍了不动杆菌属的重要有益特性,并深入探讨了它们对抗生素耐药性的新趋势。

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