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伊朗卡尚地区孕妇血清锌、血红蛋白和铁蛋白浓度及其对分娩结局的影响

Concentrations of Serum Zinc, Hemoglobin and Ferritin among Pregnant Women and their Effects on Birth Outcomes in Kashan, Iran.

作者信息

Samimi Mansoureh, Asemi Zatollah, Taghizadeh Mohsen, Azarbad Zohreh, Rahimi-Foroushani Abbas, Sarahroodi Shadi

出版信息

Oman Med J. 2012 Jan;27(1):40-5. doi: 10.5001/omj.2012.08.

Abstract

OBJECTIVES

Zinc and Iron are essential micronutrients in fetus growth and development. The aim of this study was to assess the relationship of maternal serum Zinc, Hemoglobin and Ferritin levels with their newborns weight, height and head circumference.

METHODS

This cross sectional-analytical study carried out among pregnant women referred to Naghavi Polyclinic, Kashan, Iran from November 2009 to October 2010. One hundred and twenty-nine pregnant women in the third trimester were selected and anthropometric factors of their newborns (weight, height and head circumference) and their relation to serum Zn, Hemoglobin and Ferritin concentrations were assessed.

RESULTS

Serum Hemoglobin deficiency (<11g/dl), serum Ferritin deficiency (<12 µg/L) and serum Zn deficiency (<66 µg/dl) were present in 11 (8.5%), 9 (7%) and 9 (7%) women, respectively. The proportion of newborns with birth weight of 2500-2999 g was greater among mothers with lower Hemoglobin (<11 g/dl) compared to mothers with normal Hemoglobin (≥11 g/dl; p=0.04). Multiple regression analysis showed that among biochemical characteristics of pregnant women, serum Hemoglobin levels were positively correlated with low birth weight (β=0.26; p=0.04). But serum Zn and Ferritin levels were not significantly associated with weight, height and head circumference.

CONCLUSION

Low maternal serum hemoglobin levels are associated with low birth weight and does not have any association with birth height or head circumference; but there was no significant association between maternal serum zinc and Ferritin levels with weight, height and head circumference.

摘要

目的

锌和铁是胎儿生长发育所必需的微量营养素。本研究旨在评估孕妇血清锌、血红蛋白和铁蛋白水平与新生儿体重、身高和头围之间的关系。

方法

本横断面分析研究于2009年11月至2010年10月在伊朗卡尚的纳加维综合诊所就诊的孕妇中进行。选取129名孕晚期孕妇,评估其新生儿的人体测量因素(体重、身高和头围)及其与血清锌、血红蛋白和铁蛋白浓度的关系。

结果

血清血红蛋白缺乏(<11g/dl)、血清铁蛋白缺乏(<12µg/L)和血清锌缺乏(<66µg/dl)的女性分别有11名(8.5%)、9名(7%)和9名(7%)。血红蛋白水平较低(<11g/dl)的母亲所生出生体重在2500 - 2999g之间的新生儿比例高于血红蛋白正常(≥11g/dl)的母亲(p = 0.04)。多元回归分析显示,在孕妇的生化特征中,血清血红蛋白水平与低出生体重呈正相关(β = 0.26;p = 0.04)。但血清锌和铁蛋白水平与体重、身高和头围无显著关联。

结论

孕妇血清血红蛋白水平低与低出生体重有关,与出生身高或头围无关;但孕妇血清锌和铁蛋白水平与体重、身高和头围之间无显著关联。

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Assessment and interpretation of micronutrient status during pregnancy.
Proc Nutr Soc. 2008 Nov;67(4):437-50. doi: 10.1017/S0029665108008732.
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