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巴勒斯坦孕妇贫血和缺铁的患病率及其与妊娠结局的关联

Prevalence of Anemia and Iron Deficiency among Palestinian Pregnant Women and Its Association with Pregnancy Outcome.

作者信息

Srour Mahmoud A, Aqel Samah S, Srour Khaled M, Younis Khalid R, Samarah Fekri

机构信息

Department of Medical Laboratory Sciences, Faculty of Health Professions, Al-Quds University, East Jerusalem, State of Palestine.

Department of Biology & Biochemistry, Birzeit University, Birzeit, State of Palestine.

出版信息

Anemia. 2018 Dec 24;2018:9135625. doi: 10.1155/2018/9135625. eCollection 2018.

Abstract

BACKGROUND

Anemia is a public health problem especially among pregnant women. This study aimed to investigate the prevalence of anemia and iron deficiency among pregnant women and its association with pregnancy outcome in Hebron Governorate in southern Palestine.

METHODS

This is a cross-sectional study that included 300 pregnant women in their first trimester and 163 babies. Maternal anthropometric and socioeconomic and newborns' data were collected. Complete blood count for study subjects and maternal serum ferritin were measured.

RESULTS

The prevalence of iron deficiency anemia among pregnant women was 25.7% and 52% of them had depleted iron stores. When pregnant women were grouped into three hemoglobin (Hb) tertile groups, a significant difference was observed between maternal Hb and newborns' birth weight (= 0.009), height (= 0.022), head circumference (= 0.017), and gestational age (= 0.012). There was a significant association between maternal serum ferritin and frequency of low birth weight (= 0.001) and frequency of preterm delivery (= 0.003). No significant association was observed between maternal anthropometric measures or the socioeconomic status and pregnancy outcomes.

CONCLUSION

Iron deficiency is a moderate public health problem among the study subjects. Maternal Hb and serum ferritin significantly affect pregnancy outcomes.

摘要

背景

贫血是一个公共卫生问题,在孕妇中尤为突出。本研究旨在调查巴勒斯坦南部希布伦省孕妇贫血和缺铁的患病率及其与妊娠结局的关联。

方法

这是一项横断面研究,纳入了300名孕早期孕妇和163名婴儿。收集了孕妇的人体测量数据、社会经济数据以及新生儿数据。对研究对象进行了全血细胞计数,并检测了孕妇血清铁蛋白。

结果

孕妇缺铁性贫血的患病率为25.7%,其中52%的孕妇铁储备不足。将孕妇按血红蛋白(Hb)三分位数分组后,发现孕妇Hb与新生儿出生体重(=0.009)、身高(=0.022)、头围(=0.017)和胎龄(=0.012)之间存在显著差异。孕妇血清铁蛋白与低出生体重发生率(=0.001)和早产发生率(=0.003)之间存在显著关联。未观察到孕妇人体测量指标或社会经济状况与妊娠结局之间存在显著关联。

结论

缺铁是研究对象中一个中度的公共卫生问题。孕妇Hb和血清铁蛋白显著影响妊娠结局。

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