Walsh N, Ackerman A B
Department of Dermatopathology, New York University Medical Center, New York.
Mod Pathol. 1990 Sep;3(5):599-608.
A report by Tozawa and Ackerman (Am J Dermatopathol 9(6):474, 1987) upon a distinctive type of basal cell carcinoma with a particular type of follicular differentiation has stimulated lively correspondence in the literature of dermatopathology. The lesion in question presents itself clinically as a basal cell carcinoma on the face and histopathologically as a neoplasm typified by small size, sharp circumscription, and a unique combination of kinds of follicular differentiation, namely, follicular germs and infundibula. The principal point of contention concerning this neoplasm has been whether it is truly a special variant of basal cell carcinoma or whether it is actually a trichoepithelioma. More extensive studies of this singular neoplasm, including its occurrence in patients with nevoid basal cell carcinoma syndrome, and review of the very few portrayals of it in the literature, have consolidated our view that it is indeed a special variant of basal cell carcinoma. We now present (a) new information about an early stage in the evolution of the neoplasm in point, (b) evidence to validate classification of it as a basal cell carcinoma, and (c) a critical appraisal of other lesions that might pose problems in differential diagnosis. Finally, justification is provided for the designation "infundibulocystic basal cell carcinoma."
户泽和阿克曼（《美国皮肤病理学杂志》9(6):474, 1987）发表的一篇报告，讲述了一种具有特殊毛囊分化类型的独特基底细胞癌，这在皮肤病理学文献中引发了热烈的讨论。所述病变在临床上表现为面部的基底细胞癌，在组织病理学上则表现为一种肿瘤，其特征为体积小、边界清晰，以及存在独特的毛囊分化组合，即毛囊胚芽和漏斗部。关于这种肿瘤的主要争议点在于它究竟是基底细胞癌的一种特殊变体，还是实际上是一种毛发上皮瘤。对这种独特肿瘤进行的更广泛研究，包括其在痣样基底细胞癌综合征患者中的发生情况，以及对文献中极少数关于它的描述的回顾，巩固了我们的观点，即它确实是基底细胞癌的一种特殊变体。我们现在呈现（a）关于所讨论肿瘤早期演变的新信息，（b）将其归类为基底细胞癌的验证证据，以及（c）对可能在鉴别诊断中造成问题的其他病变的批判性评估。最后，为“漏斗状囊性基底细胞癌”这一命名提供了依据。
