高效利用质谱技术进行聚糖和糖肽结构分析。
Effective use of mass spectrometry for glycan and glycopeptide structural analysis.
机构信息
Department of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University Medical Campus, Boston, Massachusetts 02118, USA.
出版信息
Anal Chem. 2012 Apr 3;84(7):3040-8. doi: 10.1021/ac3000573. Epub 2012 Mar 6.
Abstract
Most proteins are glycosylated. Mass spectrometry methods are used for mapping glycoprotein glycosylation and detailed glycan structural determination. This technology enables precise characterization of recombinant glycoproteins in the pharmaceutical industry and academic biomedicine.
摘要
大多数蛋白质都发生了糖基化。质谱方法被用于绘制糖蛋白的糖基化图谱和详细的聚糖结构测定。这项技术使制药行业和学术生物医学领域能够对重组糖蛋白进行精确的表征。
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