Poulikakos Dimitrios, Theti Davinder, Pau Vasanti, Banerjee Debasish, Jones Daniel
Renal and Transplantation Unit, St. George's Hospital NHS Trust, London, UK.
Hemodial Int. 2012 Oct;16(4):553-5. doi: 10.1111/j.1542-4758.2012.00674.x. Epub 2012 Feb 23.
Pulmonary hypertension (PHT) is frequent in patients receiving hemodialysis (HD) and carries a high mortality. While it has been suggested that arteriovenous fistulae (AVF) may exacerbate PHT in HD patients, it has also been observed that creating AVF in patients with chronic lung disease and normal renal function may lead to improved exercise tolerance. Most of the observations regarding HD patients using echocardiography demonstrated that temporary closure of AVF improved pulmonary pressures. We present the case of a 45-year-old patient with chronic obstructive pulmonary disease on HD who experienced respiratory failure following AVF formation and underwent right heart catheterization. Severe PHT was diagnosed but transient occlusion of the fistula failed to improve the PHT. This case supports the theory that fistula creation does not exacerbate pre-existing PHT and that AVF can be the access of choice in patients with known chronic lung disease and pulmonary hypertension.
肺动脉高压(PHT)在接受血液透析(HD)的患者中很常见,且死亡率很高。虽然有人认为动静脉内瘘(AVF)可能会加重HD患者的PHT,但也观察到在慢性肺病且肾功能正常的患者中创建AVF可能会提高运动耐量。大多数关于HD患者使用超声心动图的观察表明,临时闭合AVF可改善肺压力。我们报告一例45岁接受HD的慢性阻塞性肺疾病患者,其在AVF形成后发生呼吸衰竭并接受了右心导管检查。诊断为重度PHT,但瘘管的短暂闭塞未能改善PHT。该病例支持以下理论,即创建瘘管不会加重已有的PHT,并且AVF可以是已知慢性肺病和肺动脉高压患者的首选通路。