Department of Dermatology, Okayama Graduate School of Medicine, Okayama, Japan.
Eur J Dermatol. 2012 May-Jun;22(3):380-3. doi: 10.1684/ejd.2012.1665.
In a series of patients with Epstein-Barr virus (EBV)-associated hydroa vacciniforme (HV) and related disorders, we reviewed the incidence of oculomucosal and gastrointestinal involvement. Of 63 patients with EBV-related HV and/or hypersensitivity to mosquito bites (HMB), 11 patients (17.5%) presented with mucosal lesions such as aphthous stomatitis and ulcerative gingivitis, 3 patients (4.8%) had ocular symptoms including iritis, conjunctival hyperemia and corneal erosions, and 2 patients (3.2%) presented with severe HV complicated gastrointestinal involvement. Oculomucosal lesions are sometimes complicated in patients with EBV-related HV and HMB, and gastrointestinal involvement may occur in the severe form.
在一系列与 EBV 相关的水疱样疹（HV）和相关疾病的患者中，我们回顾了眼-黏膜和胃肠道受累的发生率。在 63 例 EBV 相关 HV 和/或蚊虫叮咬过敏（HMB）的患者中，11 例（17.5%）患者出现黏膜病变，如口疮性口炎和溃疡性牙龈炎，3 例（4.8%）患者出现眼部症状，包括虹膜炎、结膜充血和角膜侵蚀，2 例（3.2%）患者出现严重 HV 合并胃肠道受累。眼-黏膜病变在 EBV 相关 HV 和 HMB 患者中有时会变得复杂，胃肠道受累可能出现在严重的情况下。
