Leete E
Department of Chemistry, University of Minnesota, Minneapolis 55455.
Planta Med. 1990 Aug;56(4):339-52. doi: 10.1055/s-2006-960979.
Recent work on the biosynthesis of the tropane moiety of cocaine, hyoscamine, scopolamine, and related alkaloids is reviewed. Revision of the generally accepted biosynthetic pathway to these alkaloids is now proposed in the light of new discoveries. New information on the biosynthesis of some of the acid moieties (benzoic, tiglic and tropic acid) of the tropane ester alkaloids is also discussed.
本文综述了近期关于可卡因、莨菪碱、东莨菪碱及相关生物碱托烷部分生物合成的研究工作。鉴于新的发现，现提出对这些生物碱普遍接受的生物合成途径的修订。还讨论了托烷酯生物碱一些酸部分（苯甲酸、惕各酸和托品酸）生物合成的新信息。
