Alfred Wegener Institute for Polar and Marine Research in the Helmholtz Society, Am Handelshafen 12, 27570 Bremerhaven, Germany.
Mar Drugs. 2012 Jan;10(1):223-233. doi: 10.3390/md10010223. Epub 2012 Jan 19.
The brominated pyrrole-imidazole Ageladine A was used for live imaging of the jellyfish (jellies) Nausithoe werneri, the sea anemone Metridium senile and the flatworm Macrostomum lignano. The fluorescence properties of Ageladine A allow for estimation of pH values in tissue and organs in living animals. The results showed that Nausithoe werneri had the most acidic areas in the tentacles and close to the mouth (pH 4-6.5), Metridium senile harbours aggregates of high acidity in the tentacles (pH 5) and in Macrostomum lignano, the rhabdoids, the gonads and areas close to the mouth were the most acidic with values down to pH 5.
溴代吡咯并咪唑 Ageladine A 用于活水母（海蜇）Nausithoe werneri、海葵 Metridium senile 和扁形虫 Macrostomum lignano 的成像。Ageladine A 的荧光特性允许估计活动物组织和器官中的 pH 值。结果表明，Nausithoe werneri 的触角和靠近口部的区域酸度最高（pH 值 4-6.5），Metridium senile 的触角中聚集了高酸度（pH 值 5），而 Macrostomum lignano 的杆状体、性腺和靠近口部的区域酸度最高，pH 值低至 5。
