Campbell M, Locascio J J, Choroco M C, Spencer E K, Malone R P, Kafantaris V, Overall J E
Department of Psychiatry, New York University Medical Center, NY.
Psychopharmacol Bull. 1990;26(2):260-6.
Baseline stereotypic movements in 224 autistic children were studied as well as their relationship to certain demographic variables and measures of overall symptomatology and severity of illness. Prediction of haloperidol-related dyskinesias with measures of stereotypies and demographic variables was also attempted. Stereotypies were present in at least mild form in most children, with most showing moderate severity. Most stereotypies were in the orofacial area. I.Q. was found to be negatively related to stereotypies. Furthermore, across methods of assessment, severity and frequency of stereotypies were found to be positively related to overall symptomatology and severity of illness. No significant predictors of development of dyskinesias were found.
对224名自闭症儿童的基线刻板运动进行了研究,并探讨了其与某些人口统计学变量、总体症状学及疾病严重程度指标之间的关系。同时还尝试通过刻板行为指标和人口统计学变量来预测氟哌啶醇相关的运动障碍。大多数儿童至少存在轻度的刻板行为,多数表现为中度严重程度。大多数刻板行为出现在口面部区域。研究发现智商与刻板行为呈负相关。此外,在各种评估方法中,刻板行为的严重程度和频率与总体症状学及疾病严重程度呈正相关。未发现运动障碍发生的显著预测因素。