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主动脉根部数值模型:主动脉瓣修复术后有效瓣环高度和对合的预测。

Aortic root numeric model: annulus diameter prediction of effective height and coaptation in post-aortic valve repair.

机构信息

School of Mechanical Engineering, Tel Aviv University Faculty of Engineering, Tel Aviv, Israel.

出版信息

J Thorac Cardiovasc Surg. 2013 Feb;145(2):406-411.e1. doi: 10.1016/j.jtcvs.2012.01.080. Epub 2012 Feb 24.

Abstract

OBJECTIVE

The aim of the present study was to determine the influence of the aortic annulus (AA) diameter in order to examine the performance metrics, such as maximum principal stress, strain energy density, coaptation area, and effective height in the aortic valve.

METHODS

Six cases of aortic roots with an AA diameter of 20 and 30 mm were numerically modeled. The coaptation height and area were calculated from 3-dimensional fluid structure interaction models of the aortic valve and root. The structural model included flexible cusps in a compliant aortic root with material properties similar to the physiologic values. The fluid dynamics model included blood hemodynamics under physiologic diastolic pressures of the left ventricle and ascending aorta. Furthermore, zero flow was assumed for effective height calculations, similar to clinical measurements. In these no-flow models, the cusps were loaded with a transvalvular pressure decrease. All other parameters were identical to the fluid structure interaction models.

RESULTS

The aortic valve models with an AA diameter range of 20 to 26 mm were fully closed, and those with an AA diameter range of 28 to 30 mm were only partially closed. Increasing the AA diameter from 20 to 30 mm decreased the averaged coaptation height and normalized cusp coaptation area from 3.3 to 0.3 mm and from 27% to 2.8%, respectively. Increasing the AA diameter from 20 to 30 mm decreased the effective height from 10.9 to 8.0 mm.

CONCLUSIONS

A decreased AA diameter increased the coaptation height and area, thereby improving the effective height during procedures, which could lead to increased coaptation and better valve performance.

摘要

目的

本研究旨在确定主动脉瓣环(AA)直径的影响,以检查主动脉瓣的性能指标,如最大主应力、应变能密度、对合面积和有效高度。

方法

对直径为 20 和 30 mm 的 6 例主动脉根部进行数值建模。从主动脉瓣和根部的三维流固耦合模型中计算出对合高度和面积。结构模型包括顺应性主动脉根部中的柔性瓣叶,其材料特性与生理值相似。血流动力学模型包括左心室和升主动脉在生理舒张压下的血液流动力学。此外,为了进行有效高度计算,假设为零流量,类似于临床测量。在这些无流模型中,通过跨瓣压差对瓣叶进行加载。所有其他参数均与流固耦合模型相同。

结果

AA 直径范围为 20 至 26mm 的主动脉瓣模型完全关闭,AA 直径范围为 28 至 30mm 的模型仅部分关闭。将 AA 直径从 20 增加到 30mm 会降低平均对合高度和归一化瓣叶对合面积,分别从 3.3mm 降至 0.3mm 和从 27%降至 2.8%。将 AA 直径从 20 增加到 30mm 会使有效高度从 10.9mm 降至 8.0mm。

结论

AA 直径减小会增加对合高度和面积,从而在手术过程中提高有效高度,这可能会增加对合并改善瓣膜性能。

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