Department of Pneumology/Allergy, Ruhrlandklinik, University Hospital, Essen, Germany.
Clin Chest Med. 2012 Mar;33(1):151-63. doi: 10.1016/j.ccm.2011.12.004. Epub 2012 Jan 24.
Hypersensitivity pneumonitis (HP) is a complex syndrome caused by the inhalation of environmental antigens. Chronic HP may mimic other fibrotic lung diseases, such as idiopathic pulmonary fibrosis. Recognition of the antigen is important for diagnosis; avoidance of further exposure is critical for treatment. Fibrosis on biopsy or high-resolution computed tomography is a predictor of increased mortality. Additional research is needed to understand why the disease develops only in a minority of exposed individuals and why cases of chronic HP may progress without further antigen exposure.
过敏性肺炎（HP）是一种由吸入环境抗原引起的复杂综合征。慢性 HP 可能模仿其他纤维性肺疾病，如特发性肺纤维化。对抗原的识别对诊断很重要；避免进一步暴露对治疗至关重要。活检或高分辨率计算机断层扫描上的纤维化是死亡率增加的预测指标。需要进一步研究来了解为什么这种疾病仅在少数暴露人群中发展，以及为什么慢性 HP 病例在没有进一步抗原暴露的情况下仍会进展。
