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microRNAs 在植物应激反应中的功能。

Functions of microRNAs in plant stress responses.

机构信息

Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK 74078, USA.

出版信息

Trends Plant Sci. 2012 Apr;17(4):196-203. doi: 10.1016/j.tplants.2012.01.010. Epub 2012 Feb 23.

Abstract

The discovery of microRNAs (miRNAs) as gene regulators has led to a paradigm shift in the understanding of post-transcriptional gene regulation in plants and animals. miRNAs have emerged as master regulators of plant growth and development. Evidence suggesting that miRNAs play a role in plant stress responses arises from the discovery that miR398 targets genes with known roles in stress tolerance. In addition, the expression profiles of most miRNAs that are implicated in plant growth and development are significantly altered during stress. These later findings imply that attenuated plant growth and development under stress may be under the control of stress-responsive miRNAs. Here we review recent progress in the understanding of miRNA-mediated plant stress tolerance.

摘要

微小 RNA(miRNAs)的发现作为基因调控因子,导致了人们对动植物转录后基因调控的理解发生了范式转变。miRNAs 已成为植物生长和发育的主要调控因子。miR398 靶向具有已知应激耐受作用的基因,这一发现表明 miRNA 可能在植物应激反应中发挥作用,这为 miRNA 在植物应激反应中的作用提供了证据。此外,大多数涉及植物生长和发育的 miRNA 的表达谱在应激过程中发生显著改变。这些后来的发现意味着应激下植物生长和发育的减弱可能受到应激响应 miRNA 的控制。在这里,我们回顾了 miRNA 介导的植物抗逆性理解方面的最新进展。

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