Li Dongdong, Zeng Shuang, Dai Ruyi, Chen Kunsong
College of Agriculture and Biotechnology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China.
Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zhejiang University, Zijingang Campus, Hangzhou 310058, China.
Hortic Res. 2025 Jul 16;12(7):uhaf108. doi: 10.1093/hr/uhaf108. eCollection 2025 Jul.
The gaseous hormone ethylene controls a variety of physiological processes in horticultural plants, including fruit ripening and elongation, flower development and senescence, and responses to stresses. The functions of ethylene in these processes are intimately linked to its precise biosynthesis, which is finely tuned by a complex network of positive and negative regulators. While significant progress has been made in understanding the roles of positive regulators in ethylene biosynthesis, the negative regulators of ethylene biosynthesis has only recently begun to receive more focus. Ethylene biosynthesis is a simple two-step reaction in land plants, committed by two dedicated enzymes, 1-aminocyclopropane-1-carboxylic acid (ACC) synthase (ACS) and ACC oxidase (ACO). Over the past decade, a growing number of research has identified a wide range of transcriptional, posttranscriptional and epigenetic negative regulators for ACS and/or ACO in horticultural plants, greatly enhancing our understanding of the intricate network that modulates ethylene production. In this review, we provide a comprehensive overview of the negative regulators that mediate ethylene biosynthesis in horticultural plants, with respect to their functions and molecular mechanisms, and their responses to external environmental stimuli or internal growth signals.
气态激素乙烯控制着园艺植物中的多种生理过程，包括果实成熟与伸长、花朵发育与衰老以及对胁迫的响应。乙烯在这些过程中的功能与其精确的生物合成密切相关，而其生物合成由一个正负调控因子组成的复杂网络进行精细调节。虽然在理解乙烯生物合成中正向调控因子的作用方面已经取得了重大进展，但乙烯生物合成的负向调控因子直到最近才开始受到更多关注。在陆地植物中，乙烯生物合成是一个由两种特定酶——1-氨基环丙烷-1-羧酸（ACC）合酶（ACS）和ACC氧化酶（ACO）催化的简单两步反应。在过去十年中，越来越多的研究在园艺植物中鉴定出了大量针对ACS和/或ACO的转录、转录后和表观遗传负调控因子，极大地增进了我们对调节乙烯产生的复杂网络的理解。在这篇综述中，我们全面概述了介导园艺植物中乙烯生物合成的负调控因子，包括它们的功能和分子机制，以及它们对外部环境刺激或内部生长信号的响应。
