Vascular Anomalies Center, Hospital Italiano, Universidad de Buenos Aires, Ciudad de Buenos Aires, Argentina.
J Vasc Interv Radiol. 2012 Mar;23(3):417-22. doi: 10.1016/j.jvir.2011.12.007.
Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor and has a high mortality in newborns when associated with Kasabach-Merritt syndrome (KMS). In two newborns with KHE and severe KMS refractory to medical treatment, emergency embolization led to clinical improvement in the acute neonatal setting by reducing tumor volume, increasing the platelet count, and improving other clotting parameters. Systemic vincristine treatment was added for further tumor control. Both patients remained symptom-free at long-term follow-up.
卡波西样血管内皮细胞瘤（KHE）是一种罕见的血管肿瘤，当与卡-梅二氏综合征（KMS）相关时，新生儿的死亡率很高。在两名患有 KHE 和严重 KMS 的新生儿中，紧急栓塞通过减少肿瘤体积、增加血小板计数和改善其他凝血参数，在急性新生儿期使临床情况得到改善，对治疗产生抵抗。在进一步的肿瘤控制方面，添加了全身性长春新碱治疗。两名患者在长期随访中均无症状。
