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[HIV 阳性移民的临床流行病学特征:371 例病例研究]

[Clinico-epidemiological characteristics of HIV-positive immigrants: study of 371 cases].

作者信息

Llenas-García Jara, Rubio Rafael, Hernando Asunción, Fiorante Silvana, Maseda Diego, Matarranz Mariano, Costa José Ramón, Alonso Beatriz, Pulido Federico

机构信息

Unidad VIH, Hospital Universitario 12 de Octubre, Madrid, España.

出版信息

Enferm Infecc Microbiol Clin. 2012 Oct;30(8):441-51. doi: 10.1016/j.eimc.2012.01.009. Epub 2012 Feb 23.

Abstract

INTRODUCTION

The number of HIV-positive immigrants have increased in Spain in the last few years, and now represent a significant proportion of the epidemic. Our objective is to describe the clinico-epidemiological characteristics of HIV-positive immigrants seen in a specialist unit in Madrid.

MATERIAL AND METHODS

Retrospective study. Every patient born in a country other than Spain and attended an HIV Unit in Madrid between 1992 and 2009 was included.

RESULTS

Of the 371 patients included, 53.1% were Latin Americans, 24.5% Sub-Saharan Africans, and 22.4% others), and 60% were males. Immigrants represented 0.3% of new patients in 1992 and rose to 49.2% in 2009. The principal reason for HIV testing had been pregnancy/delivery among women (32.7%) and having a category-B disease among men (17.4%). Sexual transmission accounted for 92% of patients. Tuberculosis was the principal AIDS-diagnosing illness. Respectively 90%, 7.7%, 60%, 26.7%, 96% and 95% of patients had an IgG for HAV, HCV, Toxoplasma, Treponema, CMV and VZV. VHB-Ags+: 5.4%; PPD+: 17%. At least one syphilis episode was recorded in 62% of the men who have sex with men (MSM). Prevalence of HLA-B5701 was 6%, 0.9% and 3.8% in Caucasians, Amerindians and Afro-Americans, respectively.

CONCLUSIONS

Immigrants represent a significant proportion of new HIV-positive patients. It is a very heterogeneous group according to their clinical and epidemiological characteristics.

摘要

引言

过去几年,西班牙艾滋病毒呈阳性的移民数量有所增加,目前在这一流行病中占相当大的比例。我们的目标是描述在马德里一家专科单位就诊的艾滋病毒呈阳性移民的临床流行病学特征。

材料与方法

回顾性研究。纳入1992年至2009年间出生在西班牙以外国家并在马德里一家艾滋病毒科室就诊的每一位患者。

结果

在纳入的371名患者中,53.1%为拉丁美洲人,24.5%为撒哈拉以南非洲人,22.4%为其他地区的人,60%为男性。移民在1992年新患者中占0.3%,到2009年升至49.2%。女性进行艾滋病毒检测的主要原因是怀孕/分娩(32.7%),男性是患有乙类疾病(17.4%)。性传播占患者的92%。结核病是主要的艾滋病诊断疾病。分别有90%、7.7%、60%、26.7%、96%和95%的患者抗甲型肝炎病毒IgG、抗丙型肝炎病毒IgG、抗弓形虫IgG、抗梅毒螺旋体IgG、抗巨细胞病毒IgG和抗水痘-带状疱疹病毒IgG呈阳性。乙肝表面抗原阳性:5.4%;结核菌素试验阳性:17%。在男男性行为者(MSM)中,62%的人至少有过一次梅毒发作。白人、美洲印第安人和非裔美国人中HLA-B5701的患病率分别为6%、0.9%和3.8%。

结论

移民在新的艾滋病毒呈阳性患者中占相当大的比例。根据其临床和流行病学特征,这是一个非常多样化的群体。

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