Santiago Begoña, Blázquez Daniel, López Gala, Sainz Talía, Muñoz M, Alonso Tomás, Moro Manuel
Servicio de Pediatría, Hospital Universitario Clínico San Carlos, Madrid, España.
Enferm Infecc Microbiol Clin. 2012 Feb;30(2):64-9. doi: 10.1016/j.eimc.2011.07.010. Epub 2011 Nov 12.
The increase in immigration is changing the prevalence of mother to child infectious diseases. Our aim is to determine the serological profile of foreign pregnant women against these infections.
A retrospective cross sectional study was performed in a tertiary hospital from Madrid between August 2007 and October 2008. The seroprevalence against HIV, HBV, HCV, rubeola, T. gondii, T. pallidum and T. cruzi was determined in every pregnant immigrant, as well as in a representative group of Spanish pregnant women.
A total of 2526 immigrant and 157 Spanish pregnant women were studied. None of the Spanish and 0.5% of the foreigners showed antibodies against HIV; 18.9% of them were Sub-Saharan women. Antigen HBs was detected in 2% of the immigrant women and in 1.1% of the Spanish women. Asian women had the highest rate of type B Hepatitis (10.9%). There was 0.9% of type C Hepatitis among the immigrants and 1% among the Spanish. Within the cases with RPR ≥ 1/8, 1.6% were immigrants, most of whom were Latin American. Thirty-one per cent of the immigrants showed antibodies against T. gondii (37.5% from Central America, 2.5% from the Far East). More than 95% of the Spanish women had antibodies against Rubella, this being lower in the rest of the areas (75.5% in Sub-Saharan Africa). T. cruzi infection was detected in 12.1% of the Bolivian women studied.
The prevalence of mother-to-child transmitted infections depends on the origin of pregnant women. Knowledge of these differences may lead to improved control these diseases.
移民数量的增加正在改变母婴传染病的流行情况。我们的目的是确定外国孕妇针对这些感染的血清学特征。
2007年8月至2008年10月在马德里的一家三级医院进行了一项回顾性横断面研究。测定了每位移民孕妇以及一组具有代表性的西班牙孕妇针对艾滋病毒、乙肝病毒、丙肝病毒、风疹、弓形虫、梅毒螺旋体和克氏锥虫的血清流行率。
共研究了2526名移民孕妇和157名西班牙孕妇。西班牙孕妇中无人显示出抗艾滋病毒抗体,外国孕妇中有0.5%显示出该抗体;其中18.9%为撒哈拉以南地区的女性。在移民女性中有2%检测到乙肝表面抗原,在西班牙女性中有1.1%检测到该抗原。亚洲女性的乙型肝炎发病率最高(10.9%)。移民中有0.9%感染丙型肝炎,西班牙孕妇中有1%感染丙型肝炎。在快速血浆反应素试验(RPR)≥1/8的病例中,1.6%为移民,其中大多数是拉丁美洲人。31%的移民显示出抗弓形虫抗体(中美洲的为37.5%,远东地区的为2.5%)。超过95%的西班牙女性有抗风疹抗体,其他地区的这一比例较低(撒哈拉以南非洲为75.5%)。在所研究的玻利维亚女性中有12.1%检测到克氏锥虫感染。
母婴传播感染的流行情况取决于孕妇的原籍。了解这些差异可能有助于更好地控制这些疾病。