School of Psychology, University of Nottingham, University Park, Nottingham, NG7 2RD, United Kingdom.
Behav Brain Res. 2012 Apr 21;230(1):259-67. doi: 10.1016/j.bbr.2012.02.016. Epub 2012 Feb 17.
The involvement of the rat dorsal hippocampus (dhpc) in Pavlovian conditioning and timing of conditioned responding was examined in an appetitive preparation in which presentation of a relatively long, 40-s auditory conditioned stimulus (CS) was followed immediately by food delivery. Dorsal hippocampal lesions impaired Pavlovian conditioning in this task. They also produced a deficit in interval timing, replicating previous findings with short CSs. The conditioning and timing deficits observed are consistent with the findings from single-unit recording studies in other species, and suggest that the involvement of the dhpc in Pavlovian processes could be more general than is assumed by many of the current theories of hippocampal function.
大鼠背侧海马（dhpc）在巴甫洛夫条件反射和条件反应定时中的作用在一个有吸引力的准备中进行了检查，在这个准备中，相对较长的 40 秒听觉条件刺激（CS）的呈现立即伴随着食物的传递。背侧海马损伤损害了这个任务中的巴甫洛夫条件反射。它们还产生了在间隔时间上的缺陷，这与之前用短 CS 进行的研究结果一致。观察到的条件反射和定时缺陷与其他物种的单细胞记录研究结果一致，表明 dhpc 参与巴甫洛夫过程的作用可能比目前许多海马功能理论所假设的更为普遍。
