Department of Surgical Sciences, Anaesthesiology and Intensive Care, Uppsala University, Uppsala, Sweden.
Resuscitation. 2012 Oct;83(10):1259-64. doi: 10.1016/j.resuscitation.2012.02.018. Epub 2012 Feb 23.
The Prehospital Trauma Life Support (PHTLS) course has been widely implemented and approximately half a million prehospital caregivers in over 50 countries have taken this course. Still, the effect on injury outcome remains to be established. The objective of this study was to investigate the association between PHTLS training of ambulance crew members and the mortality in trauma patients.
A population-based observational study of 2830 injured patients, who either died or were hospitalized for more than 24 h, was performed during gradual implementation of PHTLS in Uppsala County in Sweden between 1998 and 2004. Prehospital patient records were linked to hospital-discharge records, cause-of-death records, and information on PHTLS training and the educational level of ambulance crews. The main outcome measure was death, on scene or in hospital.
Adjusting for multiple potential confounders, PHTLS training appeared to be associated with a reduction in mortality, but the precision of this estimate was poor (odds ratio, 0.71; 95% confidence interval, 0.42-1.19). The mortality risk was 4.7% (36/763) without PHTLS training and 4.5% (94/2067) with PHTLS training. The predicted absolute risk reduction is estimated to correspond to 0.5 lives saved annually per 100,000 population with PHTLS fully implemented.
PHTLS training of ambulance crew members may be associated with reduced mortality in trauma patients, but the precision in this estimate was low due to the overall low mortality. While there may be a relative risk reduction, the predicted absolute risk reduction in this population was low.
创伤院前生命支持(PHTLS)课程已被广泛实施,全球 50 多个国家/地区约有 50 万名院前急救人员参加了该课程。然而,其对伤害结局的影响仍有待确定。本研究的目的是调查急救人员接受 PHTLS 培训与创伤患者死亡率之间的关系。
这是一项基于人群的观察性研究,共纳入 2830 名受伤患者,他们在 1998 年至 2004 年期间瑞典乌普萨拉县逐步实施 PHTLS 的过程中死亡或住院时间超过 24 小时。将院前患者记录与医院出院记录、死因记录以及有关 PHTLS 培训和急救人员教育水平的信息相关联。主要结局指标是现场或医院死亡。
在调整了多个潜在混杂因素后,PHTLS 培训似乎与死亡率降低相关,但估计的精度较差(优势比,0.71;95%置信区间,0.42-1.19)。未接受 PHTLS 培训的患者死亡率为 4.7%(36/763),接受 PHTLS 培训的患者死亡率为 4.5%(94/2067)。预计每年每 10 万人完全实施 PHTLS 可减少 0.5 例死亡,这是一个预测的绝对风险降低。
急救人员接受 PHTLS 培训可能与创伤患者死亡率降低相关,但由于总体死亡率较低,该估计的精度较低。虽然可能存在相对风险降低,但该人群的预测绝对风险降低较低。