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表观遗传学:扁形动物发育生物学的关键调控因子?

Epigenetics: a key regulator of platyhelminth developmental biology?

机构信息

Institute of Biological, Environmental and Rural Sciences (IBERS), Edward Llwyd Building, Aberystwyth University, Aberystwyth, UK.

出版信息

Int J Parasitol. 2012;42(3):221-4. doi: 10.1016/j.ijpara.2012.02.003. Epub 2012 Feb 17.

DOI:10.1016/j.ijpara.2012.02.003
PMID:22366548
Abstract

The Platyhelminthes (flukes/flatworms) are a large group of derived metazoans beautifully adapted for existence in diversely challenging ecosystems. As tractable examples of development and self-regeneration or as causative agents of aquacultural, veterinary and biomedically-relevant parasitic diseases, the platyhelminths are subject to intensive inter-disciplinary research. Given the complex lifestyles exhibited by individuals within this phylum, we postulate that epigenetic processes feature in many aspects of platyhelminth lifecycle diversity, development and environmentally-driven adaptations.

摘要

扁形动物门(吸虫/扁虫)是后生动物的一个大类群,它们经过高度特化,非常适应在多样化的挑战性生态系统中生存。作为发育和自我再生的典型范例,或作为水产养殖、兽医和与生物医学相关的寄生虫病的病原体,扁形动物受到了跨学科的广泛研究。鉴于该门内的个体表现出复杂的生活方式,我们假设表观遗传过程在扁形动物生命周期多样性、发育和环境驱动的适应的许多方面都具有特征。

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