Department of Neurology and Headache Center, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Neurol Sci. 2013 Feb;34(2):205-8. doi: 10.1007/s10072-012-0986-0. Epub 2012 Feb 25.
We aimed to investigate the prevalence of cardiac right left shunts (RLS) in population-based samples of subjects with migraine with aura (n = 42), migraine without aura (n = 44) and controls without headache (n = 41). Cardiac RLS was assessed with transcranial Doppler sonography with intravenous injection of saline. Prevalence of RLS was highest in migraineurs with aura (45.2%) compared to migraineurs without aura (34.1%) and controls (41.5%). Permanent as opposed to latent RLS was more common among patients with migraine with aura (40.5%) than in patients with migraine without aura (23.3%) or controls (24.4%). Differences did not reach statistical significance between the three groups (p = 0.564 for RLS prevalence, p = 0.349 for prevalence of permanent shunts). Our data implicate a trend towards higher prevalence of RLS with larger shunts in subjects with migraine with aura.
我们旨在调查在偏头痛伴先兆（n=42）、偏头痛无先兆（n=44）和无头痛对照（n=41）人群中，心脏左右分流（RLS）的患病率。采用经颅多普勒超声静脉注射生理盐水评估心脏 RLS。与偏头痛无先兆（34.1%）和对照组（41.5%）相比，偏头痛伴先兆患者的 RLS 患病率最高（45.2%）。与偏头痛无先兆患者（23.3%）或对照组（24.4%）相比，偏头痛伴先兆患者中永久性 RLS 比潜伏性 RLS 更为常见（40.5%）。三组之间差异无统计学意义（RLS 患病率的 p 值=0.564，永久性分流患病率的 p 值=0.349）。我们的数据表明，偏头痛伴先兆患者的 RLS 患病率更高，分流更大。
