School of Nursing, Southern Illinois University Edwardsville, Edwardsville, IL, USA.
J Neurosci Nurs. 2012 Apr;44(2):66-71. doi: 10.1097/JNN.0b013e3182478cba.
The purpose of this secondary analysis was to investigate the relationships among a set of symptoms (fatigue, depression, impaired cognitive function, sleep disturbance) with pain severity and demographic variables. The sample of 40 women with relapsing-remitting multiple sclerosis completed instruments of pain, fatigue, depression, sleep disturbance, and an objective cognitive measure. Analysis identified one symptom cluster of pain, fatigue, depression, sleep disturbance, and impaired cognitive function, whereas a relationship between that symptom cluster and employment status existed. Pain severity correlated with fatigue, sleep disturbance, depression, and impaired cognitive function. Preliminary findings support providing education on symptoms to women with relapsing-remitting multiple sclerosis to ultimately guide their care.
本次二次分析旨在研究一组症状（疲劳、抑郁、认知功能障碍、睡眠障碍）与疼痛严重程度和人口统计学变量之间的关系。40 名复发性缓解型多发性硬化症女性患者完成了疼痛、疲劳、抑郁、睡眠障碍和客观认知测量的工具。分析确定了一个症状群，包括疼痛、疲劳、抑郁、睡眠障碍和认知功能障碍，而该症状群与就业状况存在关系。疼痛严重程度与疲劳、睡眠障碍、抑郁和认知功能障碍相关。初步研究结果支持向复发性缓解型多发性硬化症女性患者提供症状教育，最终指导其护理。
