Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Res Nurs Health. 2010 Oct;33(5):398-412. doi: 10.1002/nur.20396.
We compared the explanatory power of two symptom clusters that consisted of either three or five symptoms as correlates of physical activity in individuals with relapsing-remitting multiple sclerosis (RRMS; N = 218). The data were primarily analyzed using covariance modeling in Mplus 3.0. A symptom cluster of fatigue, depression, and pain had a moderate, negative relationship with physical activity, and this relationship was comparable in magnitude with a symptom cluster of fatigue, depression, pain, perceived cognitive dysfunction, and poor sleep quality. The relationships were attenuated after controlling for exercise history and neurological impairment. Such findings further support the consideration of a narrowly defined cluster of three symptoms as an independent correlate of physical activity in persons with RRMS.
我们比较了由三个或五个症状组成的两个症状群，以评估其在复发性缓解型多发性硬化症（RRMS；N=218）患者中的身体活动相关性。数据主要使用 Mplus 3.0 中的协方差建模进行分析。疲劳、抑郁和疼痛的症状群与身体活动呈中度负相关，与疲劳、抑郁、疼痛、认知功能障碍和睡眠质量差的症状群的相关性相当。在控制运动史和神经损伤后，这些关系减弱。这些发现进一步支持将狭义定义的三个症状群作为 RRMS 患者身体活动的独立相关因素的考虑。
