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紫外线暴露与非霍奇金淋巴瘤:有益还是有害影响?

Ultraviolet exposure and non-Hodgkin's lymphoma: beneficial and adverse effects?

出版信息

Cancer Causes Control. 2012 Apr;23(4):653-5; author reply 657-8. doi: 10.1007/s10552-012-9929-6. Epub 2012 Feb 26.

Abstract

Studies of risk of non-Hodgkin's lymphoma have found both direct and inverse correlations with respect to solar ultraviolet (UV) doses. Reduced risk is generally found in midlatitudes, while increased risk is generally found at higher latitudes. It is suggested that reduced risk arises from vitamin D production from UVB irradiance, while increased risk arises from immunosuppression associated with UVA irradiance. The ratio of UVA to UVB increases with increasing latitude.

摘要

关于非霍奇金淋巴瘤的风险研究发现,其与太阳紫外线(UV)剂量之间存在直接和反比关系。在中纬度地区,风险通常会降低,而在高纬度地区,风险通常会增加。据认为,风险降低是由于 UVB 辐射产生的维生素 D,而风险增加是由于 UVA 辐射引起的免疫抑制。随着纬度的增加,UVA 与 UVB 的比值增加。

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