Laboratory of Neuroscience, Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, Brazil.
Int J Geriatr Psychiatry. 2013 Jan;28(1):34-40. doi: 10.1002/gps.3787. Epub 2012 Feb 27.
The Montreal Cognitive Assessment (MoCA) is a brief cognitive schedule that has been developed for the screening of patients with Mild Cognitive Impairment (MCI). MCI is recognized as a high-risk state for Alzheimer's disease. The aim of the present study is to examine the reliability and validity of the Brazilian version of the MoCA test (MoCA-BR) in a sample of older individuals with at least 4 years of education.
The MoCA-BR was administered to 112 older adults who were classified into three diagnostic groups according to their cognitive state (Alzheimer's disease, n = 28; MCI, n = 43; normal controls, n = 41). This procedure was based on clinical and neuropsychological data. The performance in the MoCA-BR was compared with the Mini-mental state examination (MMSE) and the Cambridge Cognitive Examination. Diagnostic accuracy was examined with the receiver operating characteristic (ROC) curve analyses.
Cronbach's alpha for the MoCA-BR was 0.75. Temporal stability (retesting after 3 months) using intraclass correlation coefficient was 0.75 (p < 0.001). The sensitivity and specificity of the MoCA-BR for MCI were 81% and 77%, respectively, with a cut-off score of 25 points. The area under the ROC curve for predicting MCI was 0.82 ± 0.06.
The present results indicate that the MoCA-BR maintains its core diagnostic properties rendering it a valid and reliable tool for the screening of MCI among older individuals with at least 4 years of education.
蒙特利尔认知评估（MoCA）是一种简短的认知量表，专为轻度认知障碍（MCI）患者的筛查而开发。MCI 被认为是阿尔茨海默病的高危状态。本研究旨在检验具有至少 4 年教育程度的老年个体中 MoCA 测试的巴西版本（MoCA-BR）的可靠性和有效性。
MoCA-BR 被用于 112 名老年人，他们根据认知状态分为三组：阿尔茨海默病组（n = 28）、MCI 组（n = 43）和正常对照组（n = 41）。这一过程基于临床和神经心理学数据。MoCA-BR 的表现与简易精神状态检查（MMSE）和剑桥认知测验进行了比较。诊断准确性通过接收者操作特征（ROC）曲线分析进行了检验。
MoCA-BR 的 Cronbach's alpha 为 0.75。使用组内相关系数进行的时间稳定性（3 个月后重测）为 0.75（p < 0.001）。MoCA-BR 对 MCI 的敏感性和特异性分别为 81%和 77%，截断分数为 25 分。预测 MCI 的 ROC 曲线下面积为 0.82 ± 0.06。
本研究结果表明，MoCA-BR 保持了其核心诊断特性，使其成为具有至少 4 年教育程度的老年个体中 MCI 筛查的有效且可靠的工具。
