Rahman Tomader Taha Abdel, El Gaafary Maha Mohamed
Geriatric Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Geriatr Gerontol Int. 2009 Mar;9(1):54-61. doi: 10.1111/j.1447-0594.2008.00509.x.
Mild cognitive impairment (MCI) is a clinical label which includes elderly subjects with memory impairment and with no significant daily functional disability. MCI is an important target for Alzheimer's dementia prevention studies. Data on the prevalence and incidence of MCI varies greatly according to cultural difference. The first aim of this study was to assess the reliability and validity of Montreal Cognitive Assessment (MoCA) Arabic version in MCI detection. The second was to determine the prevalence of MCI among apparently healthy elderly people attending geriatric clubs in Cairo.
In stage I reliability & validity of MoCA Arabic version were assessed in reference to Cambridge Cognitive Examination (CAMCOG). In stage II prevalence of MCI was estimated using Arabic MoCA among apparently healthy elderly attending geriatric clubs. These geriatric clubs were randomly selected from different regions in Cairo governorate.
Test-retest reliability data of the Arabic MoCA were collected approximately 35.0 +/- 17.6 days apart. The mean change in Arabic MoCA scores from the first to second evaluation was 0.9 +/- 2.5 points, and correlation between the two evaluations was high (correlation coefficient = 0.92, P < 0.001). The internal consistency of the Arabic MoCA was good, yielding a Cronbach's alpha on the standardized items of 0.83. In diagnosing mild cognitive impairment, the Arabic MoCA showed 92.3% sensitivity and 85.7% specificity. The prevalence of MCI among elderly subjects attending geriatric clubs in Cairo is 34.2% and 44.3% of healthy men and women, respectively.
Older age, female sex and less education are the independent risk factors for MCI among apparently healthy elderly subjects attending geriatric clubs in Cairo.
轻度认知障碍（MCI）是一个临床标签，包括有记忆障碍且日常功能无明显残疾的老年人。MCI是阿尔茨海默病痴呆预防研究的重要目标。根据文化差异，MCI的患病率和发病率数据差异很大。本研究的首要目的是评估蒙特利尔认知评估（MoCA）阿拉伯语版本在MCI检测中的可靠性和有效性。第二个目的是确定开罗老年俱乐部中看似健康的老年人中MCI的患病率。
在第一阶段，参照剑桥认知检查（CAMCOG）评估MoCA阿拉伯语版本的可靠性和有效性。在第二阶段，使用阿拉伯语MoCA对开罗老年俱乐部中看似健康的老年人进行MCI患病率评估。这些老年俱乐部是从开罗省不同地区随机选取的。
阿拉伯语MoCA的重测信度数据收集时间间隔约为35.0±17.6天。从第一次评估到第二次评估，阿拉伯语MoCA分数的平均变化为0.9±2.5分，两次评估之间的相关性很高（相关系数=0.92，P<0.001）。阿拉伯语MoCA的内部一致性良好，标准化项目的克朗巴哈系数为0.83。在诊断轻度认知障碍时，阿拉伯语MoCA的敏感性为92.3%，特异性为85.7%。开罗老年俱乐部中老年人的MCI患病率分别为34.2%，其中健康男性占44.3%，健康女性占44.3%。
在开罗老年俱乐部中看似健康的老年人中，年龄较大、女性和受教育程度较低是MCI的独立危险因素。
