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在南非社区样本中,蒙特利尔认知评估量表与可重复神经心理状态评估量表作为认知筛查工具的一致性。

The concordance between the Montreal cognitive assessment and the repeatable battery for the assessment of neuropsychological status as a cognitive screening tool in a south African community sample.

作者信息

Suliman Sharain, Bröcker Erine, Beath Natalie, Van den Heuvel Leigh L, Asmal Laila, Kilian Sanja, Emsley Robin, Carr Jonatha, Seedat Soraya

机构信息

Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

South African Medical Research Council Unit on the Genomics of Brain Disorders, Department of Psychiatry, Stellenbosch University, Cape Town, South Africa.

出版信息

Glob Ment Health (Camb). 2025 Aug 8;12:e96. doi: 10.1017/gmh.2025.10050. eCollection 2025.

Abstract

We aimed to compare the concordance between the Montreal Cognitive Assessment (MoCA) and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), as cognitive screening tools to detect mild cognitive impairment (MCI) in a South African adult community sample ( = 370). The MoCA showed acceptable internal consistency, agreement with the RBANS and good criterion-related validity. The MoCA demonstrated fair performance, compared to the RBANS, for predicting MCI, with AUCs of 0.711 (English) and 0782 (Afrikaans). Using the recommended cut-off score of 26/30, the MoCA showed high sensitivity but low specificity. Sensitivity and specificity were optimal when the cut-off scores were lowered to 25/30 (English) and 24/30 (Afrikaans). MoCA scores were significantly associated with language, sex, age and education. While these findings demonstrate applicability of the MoCA in screening for and identifying mild cognitive difficulty in this population, our findings suggest that modifications are needed to improve differentiating between normal aging and MCI. Until a culturally adapted version of the MoCA is developed and validated for this population we suggest lowering the cut-off score to 25/30 (English) and 24/30 (Afrikaans) to reduce false positive NCD diagnoses. Demographic factors (age, sex, language and education) also need to be considered.

摘要

我们旨在比较蒙特利尔认知评估量表(MoCA)与可重复神经心理状态评估量表(RBANS)之间的一致性,将其作为认知筛查工具,用于检测南非一个成年社区样本(n = 370)中的轻度认知障碍(MCI)。MoCA显示出可接受的内部一致性、与RBANS的一致性以及良好的效标关联效度。与RBANS相比,MoCA在预测MCI方面表现尚可,英文版本的曲线下面积(AUC)为0.711,南非荷兰语版本为0.782。使用推荐的26/30的临界值时,MoCA显示出高敏感性但低特异性。当临界值降至25/30(英文)和24/30(南非荷兰语)时,敏感性和特异性最佳。MoCA得分与语言、性别、年龄和教育程度显著相关。虽然这些结果表明MoCA在该人群中筛查和识别轻度认知困难方面具有适用性,但我们的研究结果表明,需要进行修改以改善正常衰老与MCI之间的区分。在针对该人群开发并验证文化适应性版本的MoCA之前,我们建议将临界值降至25/30(英文)和24/30(南非荷兰语)以减少非认知障碍(NCD)的假阳性诊断。还需要考虑人口统计学因素(年龄、性别、语言和教育程度)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d2e/12394016/a88ed83ab2ba/S2054425125100502_fig1.jpg

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