Gilbert Allison R, Morrissey Joseph P, Domino Marisa E
Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
J Dual Diagn. 2011 Jul;7(3):117-129. doi: 10.1080/15504263.2011.592411.
The current study examined whether clinical responses to an integrated treatment intervention among women with co-occurring disorders and histories of abuse varied according to their service use patterns at baseline. METHODS: Data were from a national, multi-site, integrated treatment intervention study in 1998-2003. Analyses included 999 study participants assigned to the integrated treatment group and who were symptomatic at baseline. Participants' baseline service use activity was characterized according to five distinct baseline service use clusters. Logistic regression models estimated study participants' odds of good clinical responses to integrated treatment at 12 months across the five service clusters. RESULTS: Participants with high levels of psychotropic medication and medical care use at baseline had significantly lower odds than low-intensity service users of having a good response to integrated treatment at 12 months on mental health, alcohol addiction, and posttraumatic stress measures. A majority of women in this group had serious medical illness or disability and were more likely than their counterparts with other service use patterns to have used homeless or domestic violence shelters. CONCLUSIONS: Women who used high levels of medication and medical services appear to have faced especially difficult barriers in responding well to integrated treatment. Careful assessments of their mental health, trauma, and medical treatment needs may be required as part of integrated treatment in an effort to improve their response to integrated treatment, clinical outcomes and well-being. This information can also be used to target integrated treatment to women who are likely to respond positively and achieve meaningful improvements in their functioning.
本研究探讨了患有共病及有虐待史的女性对综合治疗干预的临床反应是否因其基线服务使用模式而异。方法:数据来自1998 - 2003年一项全国性、多地点的综合治疗干预研究。分析纳入了999名被分配到综合治疗组且在基线时有症状的研究参与者。参与者的基线服务使用活动根据五个不同的基线服务使用集群进行了特征描述。逻辑回归模型估计了研究参与者在五个服务集群中12个月时对综合治疗有良好临床反应的几率。结果:在基线时使用高水平精神药物和医疗护理的参与者,在心理健康、酒精成瘾和创伤后应激测量方面,12个月时对综合治疗有良好反应的几率显著低于低强度服务使用者。该组中的大多数女性患有严重的疾病或残疾,并且比具有其他服务使用模式的女性更有可能使用过无家可归者或家庭暴力庇护所。结论:使用高水平药物和医疗服务的女性在对综合治疗产生良好反应方面似乎面临特别困难的障碍。作为综合治疗的一部分,可能需要对她们的心理健康、创伤和医疗需求进行仔细评估,以努力改善她们对综合治疗的反应、临床结果和幸福感。这些信息还可用于针对可能产生积极反应并在其功能方面取得有意义改善的女性进行综合治疗。