Ghorbani Gholam Ali
Department of Infectious Diseases, Baqiyatallah Research Center for Gastroenterology and Liver Diseases, Tehran, IR Iran.
Hepat Mon. 2011 Dec;11(12):955-7. doi: 10.5812/kowsar.1735143X.764. Epub 2011 Dec 20.
Hepatitis A virus (HAV) infection is one of the most common causes of acute hepatitis and it is a serious health problem worldwide. HAV infection is a vaccine preventable disease that can produce the lifelong immunity seen in many developed countries with the vaccination schedule administered to children; however this vaccine is not used in developing countries at the present time. Improvements in food and water hygiene have caused a displacement of hepatitis A infection from children to adults which has increased mortality rates. Therefore evaluation of HAV immunity levels can help health authorities develop polices for prophylaxis especially in developing countries.
甲型肝炎病毒（HAV）感染是急性肝炎最常见的病因之一，也是全球范围内严重的健康问题。HAV感染是一种可通过疫苗预防的疾病，在许多发达国家，按照儿童疫苗接种计划接种疫苗后可产生终身免疫力；然而，目前发展中国家并未使用这种疫苗。食品和水卫生条件的改善导致甲型肝炎感染人群从儿童转向成人，这增加了死亡率。因此，评估HAV免疫水平有助于卫生当局制定预防政策，特别是在发展中国家。
