Izadi Morteza, Esfahani Ali Aliakbar, Hassannia Hadi, Jonaidi Jafari Nematollah, Rahmati Najarkolaei Fatemeh, Rezaee-Zavareh Mohammad Saeid
Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Gastroenterol Hepatol Bed Bench. 2016 Spring;9(2):100-4.
This study aims to investigate the seroprevalence of HAV immunity among Iranian soldiers and determine whether vaccination should be given to military draftees.
Hepatitis A virus (HAV) is highly contagious in individuals living in crowded conditions such as military centers. To the best of our knowledge, there are limited data about HAV prevalence among Iranian soldiers.
In this cross-sectional study, a total of 1554 soldiers were recruited through a random clustering sampling. Serum anti-HAV antibody was measured by Enzyme-linked immunosorbent assay (ELISA). Statistical analysis was performed using SPSS.
A total of 1554 male soldiers with age ranged from 18 to 34 years (mean age: 21.2±1.9 years) at baseline were evaluated. Overall, 80.3% of the analyzed specimens were anti-HAV seropositive. Seroprevalence rates significantly increased with the age.
Our results suggest that vaccination for HAV is not necessary for Iranian military draftees. However, the vaccination is recommended for high-risk groups, including anti-HAV seronegative soldiers.
本研究旨在调查伊朗士兵中甲型肝炎病毒(HAV)免疫的血清流行率,并确定是否应对应征入伍士兵进行疫苗接种。
甲型肝炎病毒(HAV)在生活在军事中心等拥挤环境中的个体中具有高度传染性。据我们所知,关于伊朗士兵中HAV流行率的数据有限。
在这项横断面研究中,通过随机整群抽样招募了总共1554名士兵。采用酶联免疫吸附测定(ELISA)检测血清抗-HAV抗体。使用SPSS进行统计分析。
基线时共评估了1554名年龄在18至34岁之间(平均年龄:21.2±1.9岁)的男性士兵。总体而言,80.3%的分析样本抗-HAV血清学呈阳性。血清流行率随年龄显著增加。
我们的结果表明,伊朗应征入伍士兵无需接种HAV疫苗。然而,建议对包括抗-HAV血清阴性士兵在内的高危人群进行疫苗接种。