Jacquemyn Y, Michiels I, Martens G
Antwerp University Hospital, Edegem.
J Obstet Gynaecol. 2012 Apr;32(3):257-9. doi: 10.3109/01443615.2011.645091.
The aim of this study was to compare the risk of secondary caesarean section in induced versus spontaneous labour in the second delivery of low risk women who had a vaginal delivery in their first pregnancy. The data were retrospective cohort from an existing regional database, comparing term (between 37 and 42 gestational weeks) second deliveries in cephalic position in women who had previously given vaginal birth. Diabetes, hypertension and multiple pregnancy were excluded as were those with a birth weight less than 2500 g or more than 4500 g. The difference was not significant when induction was performed after 41 weeks. The results showed a total number of 29693 deliveries were included, 21243 in spontaneous labour and 8450 after induction of labour. In the spontaneous group 312 (1.5%) underwent secondary caesarean section, as compared to 237 (2.8%) in the induced group, p < 0.001, OR 1.93 (95% confidence interval 1.63-2.29). It was concluded that elective induction of labour in low risk women who have previously given vaginal birth is associated with an almost doubled rate of secondary caesarean section if performed before 41 weeks.
本研究的目的是比较首次妊娠经阴道分娩的低风险女性再次分娩时,引产与自然分娩的二次剖宫产风险。数据来自现有的区域数据库中的回顾性队列研究,比较既往经阴道分娩的女性足月(妊娠37至42周)头位二次分娩情况。排除患有糖尿病、高血压、多胎妊娠以及出生体重低于2500g或高于4500g的女性。41周后进行引产时差异不显著。结果显示,共纳入29693例分娩,其中自然分娩21243例,引产8450例。自然分娩组中有312例(1.5%)接受了二次剖宫产,引产组为237例(2.8%),p<0.001,比值比为1.93(95%置信区间1.63 - 2.29)。研究得出结论,如果在41周前进行引产,既往经阴道分娩的低风险女性选择性引产与二次剖宫产率几乎翻倍相关。