UCLH Head and Neck Centre, London, UK.
Photodiagnosis Photodyn Ther. 2012 Mar;9(1):83-6. doi: 10.1016/j.pdpdt.2011.12.002. Epub 2012 Jan 14.
We report on the application of photodynamic therapy (PDT) in the management of Kimura disease. A 58-year-old Asian male was offered this modality to assess the possibility to control disease progression. The patient was managed with surgery and the disease recurred and caused facial disfigurement. PDT was offered after careful discussion at UCLH multidiscipline meeting. The photosensitiser "mTHPC" was introduced intravenously 96h prior to delivering the light under ultrasound guidance. Magnetic resonance images showed moderate-significant reduction of the disease volume. Fourteen months post-PDT, the disease started re-growing and the patient subsequently underwent one further round of PDT which was as successful as the first round in reducing the facial disfigurement. Photodynamic therapy was very effective in controlling disease progression in this patient who suffers from Kimura disease.
我们报告了光动力疗法（PDT）在金伯病治疗中的应用。一位 58 岁的亚洲男性接受了这种治疗方法，以评估控制疾病进展的可能性。该患者接受了手术治疗，但疾病复发并导致面部畸形。在 UCLH 多学科会议上进行了仔细讨论后，为患者提供了 PDT。在静脉注射光敏剂“mTHPC”96 小时后，在超声引导下进行光疗。磁共振成像显示疾病体积有中度显著缩小。PDT 治疗后 14 个月，疾病开始再次生长，随后患者接受了一轮新的 PDT，与第一轮治疗一样成功地减少了面部畸形。光动力疗法在控制该金伯病患者的疾病进展方面非常有效。
