Luo Guangming, Gu Feifei, Liu Tianlin, Huang Yuanliang
Shanghai Engineering Research Center of Tooth Restoration and Regeneration, School of Stomatology, Tongji University, Shanghai 200072, P.R. China.
Department of Stomatology, Shanghai East Hospital Affiliated with Tongji University, Shanghai 200120, P.R. China.
Exp Ther Med. 2016 Jan;11(1):218-220. doi: 10.3892/etm.2015.2901. Epub 2015 Nov 27.
Kimura's disease (KD), a chronic inflammatory disease of uncertain etiology, manifests as a painless subcutaneous swelling in the head and neck region that involves major salivary glands and regional lymph nodes. To date, the majority of cases of KD have been documented in Asian males aged 20-30 years. However, the number of reported cases of KD involving the oral and maxillofacial area is limited, and since the masses appear similar to cysts or benign tumors, the establishment of an accurate pre-operative diagnosis is challenging. The accurate diagnosis of KD is considered to require surgical excision followed by histopathological examination. In the current case, a 39-year-old man was admitted to hospital in October 2011 with a swelling evident on his right cheek. Surgical excision was performed, and histopathological observation was carried out. The formation of a lymphoid nodule accompanied by the vigorous proliferation of small blood vessels, eosinophilic infiltration and thickened cell walls were observed. No sign of recurrence of the mass has yet been observed, on the basis of the telephone follow-up interviews. These findings provide a novel insight useful in the diagnosis of KD in the oral and maxillofacial area.
木村病(KD)是一种病因不明的慢性炎症性疾病,表现为头颈部无痛性皮下肿胀,累及主要唾液腺和区域淋巴结。迄今为止,大多数木村病病例见于20至30岁的亚洲男性。然而,报道的累及口腔颌面部的木村病病例数量有限,且由于肿块外观类似于囊肿或良性肿瘤,术前准确诊断具有挑战性。木村病的准确诊断被认为需要手术切除并进行组织病理学检查。在本例中,一名39岁男性于2011年10月因右脸颊明显肿胀入院。进行了手术切除,并进行了组织病理学观察。观察到形成了淋巴小结,伴有小血管的旺盛增生、嗜酸性粒细胞浸润和细胞壁增厚。根据电话随访访谈,尚未观察到肿块复发的迹象。这些发现为口腔颌面部木村病的诊断提供了新的见解。