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硝酸铅对印度胡鲶肾脏和卵巢中几种酶活性的影响

Effects of lead nitrate on the activities of a few enzymes in the kidney and ovary Heteropneustes fossillis.

作者信息

Sastry K V, Agrawal M K

出版信息

Bull Environ Contam Toxicol. 1979 May;22(1-2):55-9. doi: 10.1007/BF02026907.

Abstract

The effect of LC(50) and a sublethal concentration of lead nitrate on the activities of alkaline phosphatase, acid phosphatase, glucose-6-phosphatase, lipase and urease in the kidneys and ovaries of a teleost fish, Channa punctatus has been examined after 96 hr and 30 days respectively. The results show that all the five enzymes in the two tissues are inhibited significantly at both the experimental stages. However, the inhibition produced after 30 days by the sublethal concentration ish higher indicating the cumulative action of lead. Further, the inhibition of enzymes is, more marked in kidney than in the ovary.

摘要

分别在96小时和30天后,检测了硝酸铅的半数致死浓度(LC50)和亚致死浓度对一种硬骨鱼——斑鳢肾脏和卵巢中碱性磷酸酶、酸性磷酸酶、葡萄糖-6-磷酸酶、脂肪酶和脲酶活性的影响。结果表明,在两个实验阶段,两种组织中的所有五种酶均受到显著抑制。然而,亚致死浓度在30天后产生的抑制作用更强,表明铅具有累积作用。此外,酶的抑制在肾脏中比在卵巢中更明显。

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