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恒磨牙釉质发育不全和乳前牙釉质发育不全。

Deciduous molar hypomineralization and molar incisor hypomineralization.

机构信息

Department of Cariology, Endodontology and Pedodontology, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands.

出版信息

J Dent Res. 2012 Jun;91(6):551-5. doi: 10.1177/0022034512440450. Epub 2012 Feb 27.

Abstract

This study was embedded in the Generation R Study, a population-based prospective cohort study from fetal life until young adulthood. This study focused on the relationship between Deciduous Molar Hypomineralization (DMH) and Molar Incisor Hypomineralization (MIH). First permanent molars develop during a period similar to that of second primary molars, with possible comparable risk factors for hypomineralization. Children with DMH have a greater risk of developing MIH. Clinical photographs of clean, moist teeth were taken with an intra-oral camera in 6,161 children (49.8% girls; mean age 74.3 mos, SD ± 5.8). First permanent molars and second primary molars were scored with respect to DMH or MIH. The prevalence of DMH and MIH was 9.0% and 8.7% at child level, and 4.0% and 5.4% at tooth level. The Odds Ratio for MIH based on DMH was 4.4 (95% CI, 3.1-6.4). The relationship between the occurrence of DMH and MIH suggests a shared cause and indicates that, clinically, DMH can be used as a predictor for MIH.

摘要

本研究嵌入了“生育队列研究”,这是一项从胎儿期到成年早期的基于人群的前瞻性队列研究。本研究侧重于乳牙龋齿(DMH)和恒切牙釉质发育不全(MIH)之间的关系。第一恒磨牙在与第二乳磨牙相似的时期发育,可能具有类似的矿化不全的危险因素。患有 DMH 的儿童发生 MIH 的风险更大。在 6161 名儿童(49.8%为女孩;平均年龄 74.3 个月,标准差 ± 5.8)中,使用口腔内相机拍摄了清洁、湿润牙齿的临床照片。第一恒磨牙和第二乳磨牙根据 DMH 或 MIH 进行评分。以儿童为单位,DMH 和 MIH 的患病率分别为 9.0%和 8.7%,以牙齿为单位,DMH 和 MIH 的患病率分别为 4.0%和 5.4%。基于 DMH 的 MIH 的优势比为 4.4(95%CI,3.1-6.4)。DMH 和 MIH 的发生之间的关系表明存在共同的病因,并表明临床上 DMH 可作为 MIH 的预测指标。

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