Delerue O, Destée A
Service de Clinique Neurologique, CHU, Lille.
Rev Neurol (Paris). 1990;146(8-9):515-7.
The natural course of untreated neuroleptic malignant syndrome (NMS) does not usually exceed 3 weeks. Its duration is reduced by dantrolene and/or bromocriptine. We report a patient in whom NMS developed after an injection of haloperidol decanoate and fluctuated during 3 months. This was due perhaps because the initial treatment with oral neuroleptic was pursued, or because the doses of dantrolene were insufficient.
未经治疗的抗精神病药恶性综合征(NMS)的自然病程通常不超过3周。丹曲林和/或溴隐亭可缩短其病程。我们报告1例患者,在注射癸酸氟哌啶醇后发生NMS,并在3个月内病情波动。这可能是因为继续采用口服抗精神病药进行初始治疗,或者是因为丹曲林剂量不足。