Krefting Research Centre, Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 424, SE-405 30 Gothenburg, Sweden.
Br J Dermatol. 2012 Jun;166(6):1301-8. doi: 10.1111/j.1365-2133.2012.10904.x. Epub 2012 May 14.
In contrast to asthma and rhinitis, few studies among adults investigating the prevalence and risk factors of eczema have been published.
To investigate the prevalence and risk factors of eczema among adults in West Sweden. A further aim was to study the associations between asthma, rhinitis and eczema.
A questionnaire on respiratory health was mailed in 2008 to 30,000 randomly selected subjects in West Sweden aged 16-75 years; 62% responded. The questionnaire included questions about eczema, respiratory symptoms and diseases and their possible determinants. A subgroup of 669 subjects underwent skin prick testing against common airborne allergens.
'Eczema ever' was reported by 40·7% and 'current eczema' by 11·5%. Both conditions were significantly more common among women. The prevalence decreased with increasing age. The coexistence of both asthma and rhinitis with eczema was common. The main risk factors were family history of allergy and asthma. The dominant environmental risk factor was occupational exposure to gas, dust or fumes. Smoking increased the risk. Eczema was associated with urbanization, while growing up on a farm was associated with a decreased risk. Added one by one to the multivariate model, asthma, allergic rhinitis and any positive skin prick test were associated with eczema.
Eczema among adults is a common disease with more women than men having and having had eczema. Eczema is associated with other atopic diseases and with airway symptoms. Hereditary factors and exposure to gas, dust and fumes are associated with eczema.
与哮喘和鼻炎相比,针对成年人的特应性皮炎患病率及其危险因素的研究较少。
研究瑞典西部成年人特应性皮炎的患病率及其危险因素。进一步的目的是研究哮喘、鼻炎与特应性皮炎之间的相关性。
2008 年,我们向瑞典西部 16-75 岁的 30000 名随机选择的对象邮寄了一份关于呼吸系统健康的调查问卷;62%的对象做出了回应。调查问卷包含了特应性皮炎、呼吸症状和疾病及其可能决定因素的相关问题。669 名对象的亚组接受了常见空气过敏原的皮肤点刺试验。
40.7%的对象报告曾患有“特应性皮炎”,11.5%的对象报告目前患有“特应性皮炎”。这两种疾病在女性中更为常见。患病率随着年龄的增长而降低。同时患有哮喘和鼻炎的对象同时患有特应性皮炎的情况很常见。主要的危险因素是过敏和哮喘家族史。主要的环境危险因素是职业性接触气体、灰尘或烟雾。吸烟会增加患病风险。特应性皮炎与城市化有关,而在农场长大与患病风险降低有关。在多元模型中逐一添加,哮喘、变应性鼻炎和任何阳性皮肤点刺试验均与特应性皮炎相关。
成年人特应性皮炎是一种常见疾病,女性患者多于男性,且更多女性曾患有或正在患有特应性皮炎。特应性皮炎与其他特应性疾病和气道症状有关。遗传因素和接触气体、灰尘和烟雾与特应性皮炎有关。