Sleep and Circadian Research Group, Woolcock Institute of Medical Research, Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales, Australia.
Intern Med J. 2012 Jun;42(6):634-41. doi: 10.1111/j.1445-5994.2012.02753.x.
To determine the relationship of sleep disorders with blood pressure and obesity in a large, relatively healthy, community-based cohort.
A cross-sectional study was undertaken using data from 22,389 volunteer blood donors in New Zealand aged 16-84 years. Height, weight, neck circumference and blood pressure were measured directly, and data on sleep and other factors were ascertained using a validated self-administered questionnaire.
Even in a relatively young, non-clinical cohort, lack of sleep (34%), snoring (33%), high blood pressure (20%) and obesity (19%) are common. After adjusting for relevant confounders, participants at high risk of sleep apnoea had double the odds of having high blood pressure but only in participants over 40 years. Very low and high quantities of sleep are also associated with high blood pressure. Even after controlling for neck circumference, self-reported sleep apnoea, sleep dissatisfaction and low amounts of sleep are associated with a higher body mass index.
Obesity and hypertension have significant associations with a variety of sleep disorders, even in those less than 40 years of age and after adjusting for a wide range of potential confounders.
在一个大型的、相对健康的基于社区的队列中，确定睡眠障碍与血压和肥胖之间的关系。
对新西兰年龄在 16-84 岁的 22389 名志愿献血者进行了横断面研究。直接测量身高、体重、颈围和血压，并使用经过验证的自我管理问卷来确定睡眠和其他因素的数据。
即使在一个相对年轻、非临床的队列中，睡眠不足（34%）、打鼾（33%）、高血压（20%）和肥胖（19%）也很常见。在调整了相关混杂因素后，患有睡眠呼吸暂停高风险的参与者患高血压的几率是其他人的两倍，但仅限于 40 岁以上的参与者。睡眠时间非常少和非常多也与高血压有关。即使在控制颈围、自我报告的睡眠呼吸暂停、睡眠不满和睡眠时间少的情况下，睡眠障碍与更高的体重指数也有显著关联。
肥胖和高血压与各种睡眠障碍有显著关联，即使在年龄小于 40 岁的人群中也是如此，且在调整了广泛的潜在混杂因素后仍然如此。
