Chen Xiaoli, Pensuksan Wipawan C, Lohsoonthorn Vitool, Lertmaharit Somrat, Gelaye Bizu, Williams Michelle A
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.
School of Nursing, Walailak University, Nakhon Si Thammarat 80160, Thailand.
Int J Soc Sci Stud. 2014 Jul;2(3):89-99. doi: 10.11114/ijsss.v2i3.439.
This study aimed to examine the association between obstructive sleep apnea (OSA) and obesity among young adults. A total of 2911 college students in Thailand participated in the study. Anthropometric measurements and blood pressure were taken by trained research staff. Overall, 6.3% of college students had OSA determined by the Berlin Questionnaire, 9.6% were overweight (BMI: 25-29 kg/m), 4.5% were obese (BMI≥30 kg/m); 12.4% had abdominal obesity (men: waist circumference≥90 cm; women: waist circumference≥80 cm). There were significant associations between OSA and overweight (odds ratio (OR)=1.72; 95% confidence interval (CI)=1.04-1.85) and obesity (OR=24.23; 95% CI=15.20-38.61), independent of demographic and lifestyle factors, blood pressure, and psychological distress. Students with OSA were more likely to have abdominal obesity than those without OSA (OR=2.09; 95% CI=1.19-3.67). OSA was significantly related to joint effects of general and abdominal obesity. The OSA-obesity associations were robust and evident for both genders, individuals with normal and elevated blood pressure, and those with and without psychological distress. This study shows independent associations of OSA with general and abdominal obesity among young adults. OSA could be a risk factor for obesity and consequent cardiovascular morbidities. OSA screening and treatment might be important for young adults.
本研究旨在探讨年轻成年人中阻塞性睡眠呼吸暂停(OSA)与肥胖之间的关联。泰国共有2911名大学生参与了该研究。经过培训的研究人员进行了人体测量和血压测量。总体而言,根据柏林问卷确定,6.3%的大学生患有OSA,9.6%超重(BMI:25 - 29 kg/m),4.5%肥胖(BMI≥30 kg/m);12.4%有腹型肥胖(男性:腰围≥90 cm;女性:腰围≥80 cm)。OSA与超重(比值比(OR)=1.72;95%置信区间(CI)=1.04 - 1.85)和肥胖(OR = 24.23;95% CI = 15.20 - 38.61)之间存在显著关联,不受人口统计学和生活方式因素、血压及心理困扰的影响。患有OSA的学生比未患OSA的学生更易出现腹型肥胖(OR = 2.09;95% CI = 1.19 - 3.67)。OSA与全身肥胖和腹型肥胖的联合效应显著相关。OSA与肥胖之间的关联在男女、血压正常和血压升高者以及有和没有心理困扰的人群中均稳健且明显。本研究表明,年轻成年人中OSA与全身肥胖和腹型肥胖存在独立关联。OSA可能是肥胖及随之而来的心血管疾病的危险因素。OSA筛查和治疗对年轻成年人可能很重要。