Liechti M, Baur H R, Gurtner H P, Straub P W
Medizinische Universitätsklinik, Inselspital Bern.
Schweiz Med Wochenschr. 1990 Oct 13;120(41):1493-6.
Three young female patients with heart problems and positive serologic tests or characteristic histologic lesions for Chagas' disease (American trypanosomiasis) are reported, one of them having presented with acute anterior myocardial infarction with only minor coronary lesions. The most prominent features of the disease are discussed with emphasis on late cardiac complications. Chagas' cardiomyopathy is the leading cause of sudden death in Latin America, where an estimated 10 to 12 million people are infected in endemic areas from southern Mexico to southern Argentina. It has also been termed "emboligenic cardiomyopathy" since arterial embolism is a very frequent complication. Embolic obstruction of a coronary artery may therefore well be the most probable cause of myocardial infarction in young people with Chagas' disease, although other mechanisms cannot be excluded.
本文报告了3例患有心脏问题且查加斯病（美洲锥虫病）血清学检测呈阳性或具有特征性组织学病变的年轻女性患者，其中1例表现为急性前壁心肌梗死，冠状动脉病变轻微。本文讨论了该病最突出的特征，并重点关注了晚期心脏并发症。查加斯心肌病是拉丁美洲猝死的主要原因，在从墨西哥南部到阿根廷南部的流行地区，估计有1000万至1200万人感染。它也被称为“栓塞性心肌病”，因为动脉栓塞是一种非常常见的并发症。因此，冠状动脉的栓塞性阻塞很可能是患有查加斯病的年轻人发生心肌梗死的最可能原因，尽管不能排除其他机制。
