Characterization of metalloprotease and serine protease activities in batch CHO cell cultures: control of human recombinant IFN-γ proteolysis by addition of iron citrate.
作者信息
Clincke Marie-Françoise, Guedon Emmanuel, Yen Frances T, Ogier Virginie, Goergen Jean-Louis
机构信息
Laboratoire Réactions et Génie des Procédés UPR-CNRS 3349, ENSAIA-INPL, Nancy-Université, 54505 Vandoeuvre-lès-Nancy, France ; Lipidomix (EA4422), ENSAIA-INPL, Nancy-Université, 54505 Vandoeuvre-lès-Nancy, France ; Genclis SAS, 54505 Vandoeuvre-lès-Nancy, France.
Laboratoire Réactions et Génie des Procédés UPR-CNRS 3349, ENSAIA-INPL, Nancy-Université, 54505 Vandoeuvre-lès-Nancy, France.
出版信息
BMC Proc. 2011 Nov 22;5 Suppl 8(Suppl 8):P115. doi: 10.1186/1753-6561-5-S8-P115. eCollection 2011.
Abstract
摘要
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本文引用的文献
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In Vitro Cell Dev Biol Anim. 2005 Mar-Apr;41(3-4):83-91. doi: 10.1290/0411075.1.
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The macroheterogeneity of recombinant human interferon-gamma produced by Chinese-hamster ovary cells is affected by the protein and lipid content of the culture medium.
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