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来自大阿米芹的抗炎新香豆素

Anti-inflammatory new coumarin from the Ammi majus L.

作者信息

Selim Yasser Abdelaal, Ouf Nabil Hassan

机构信息

Faculty of Specific Education, Zagazig University, Zagazig, Egypt.

出版信息

Org Med Chem Lett. 2012 Jan 12;2(1):1. doi: 10.1186/2191-2858-2-1.

Abstract

Investigation of the aerial parts of the Egyptian medicinal plant Ammi majus L. led to isolation of new coumarin, 6-hydroxy-7-methoxy-4 methyl coumarin (2) and 6-hydroxy-7-methoxy coumarin (3); this is the first time they have been isolated from this plant. The structures of the compounds (2 &3) were elucidated by spectroscopic data interpretation and showed anti-inflammatory and anti-viral activity. GRAPHICAL An efficient, one-new coumarin (2) was isolated from the aerial parts of the A. Majus L. was evaluated for their anti-viral and anti-inflammatory activities.

摘要

对埃及药用植物大阿米芹地上部分的研究,导致分离出新型香豆素6-羟基-7-甲氧基-4-甲基香豆素(2)和6-羟基-7-甲氧基香豆素(3);这是首次从该植物中分离出它们。通过光谱数据解析阐明了化合物(2和3)的结构,并显示出抗炎和抗病毒活性。图表从大阿米芹地上部分分离出一种高效的新型香豆素(2),并对其抗病毒和抗炎活性进行了评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4753/3349536/9dd1e03dd28f/2191-2858-2-1-1.jpg

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