沉默调节蛋白与热量限制 - Suppr

Suppr

超能文献

Sirtuins and calorie restriction.

作者信息

Guarente Leonard

机构信息

Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

出版信息

Nat Rev Mol Cell Biol. 2012 Feb 29;13(4):207. doi: 10.1038/nrm3308.

DOI:10.1038/nrm3308

PMID:22374145

Abstract

摘要

相似文献

Sirtuins and calorie restriction.

Nat Rev Mol Cell Biol. 2012 Feb 29;13(4):207. doi: 10.1038/nrm3308.

Utilizing calorie restriction to evaluate the role of sirtuins in healthspan and lifespan of mice.

Methods Mol Biol. 2013;1077:303-11. doi: 10.1007/978-1-62703-637-5_20.

Sirtuins as potential targets for metabolic syndrome.

Nature. 2006 Dec 14;444(7121):868-74. doi: 10.1038/nature05486.

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction.

Genes Dev. 2006 Nov 1;20(21):2913-21. doi: 10.1101/gad.1467506.

Sir2 mediates longevity in the fly through a pathway related to calorie restriction.

Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15998-6003. doi: 10.1073/pnas.0404184101. Epub 2004 Nov 1.

Increase in activity during calorie restriction requires Sirt1.

Science. 2005 Dec 9;310(5754):1641. doi: 10.1126/science.1118357.

At the crossroad of lifespan, calorie restriction, chromatin and disease: meeting on sirtuins.

Cell Cycle. 2010 May 15;9(10):1907-12. doi: 10.4161/cc.9.10.11481.

Calorie restriction--the SIR2 connection.

Cell. 2005 Feb 25;120(4):473-82. doi: 10.1016/j.cell.2005.01.029.

Sir2-independent life span extension by calorie restriction in yeast.

PLoS Biol. 2004 Sep;2(9):E296. doi: 10.1371/journal.pbio.0020296. Epub 2004 Aug 24.

Sir-2.1 modulates 'calorie-restriction-mediated' prevention of neurodegeneration in Caenorhabditis elegans: implications for Parkinson's disease.

Biochem Biophys Res Commun. 2011 Sep 23;413(2):306-10. doi: 10.1016/j.bbrc.2011.08.092. Epub 2011 Aug 26.

引用本文的文献

Mitochondrial sirtuin 4 shapes the intestinal microbiota of Drosophila by controlling lysozyme expression.

Anim Microbiome. 2025 Jun 13;7(1):63. doi: 10.1186/s42523-025-00431-x.

Inflammation and DNA damage: cause, effect or both.

Nat Rev Rheumatol. 2023 Apr;19(4):200-211. doi: 10.1038/s41584-022-00905-1. Epub 2023 Feb 7.

Chrononutrition-When We Eat Is of the Essence in Tackling Obesity.

Nutrients. 2022 Nov 29;14(23):5080. doi: 10.3390/nu14235080.

Yeast mismatch repair components are required for stable inheritance of gene silencing.

PLoS Genet. 2020 May 29;16(5):e1008798. doi: 10.1371/journal.pgen.1008798. eCollection 2020 May.

Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins.

J Biol Chem. 2016 Jul 8;291(28):14677-94. doi: 10.1074/jbc.M116.726307. Epub 2016 May 18.

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.

Nat Commun. 2015 Apr 14;6:6656. doi: 10.1038/ncomms7656.

SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence.

Aging Cell. 2014 Oct;13(5):890-9. doi: 10.1111/acel.12247. Epub 2014 Jul 18.

The controversial world of sirtuins.

Drug Discov Today Technol. 2014 Jun;12:e9-e17. doi: 10.1016/j.ddtec.2012.08.003.

Novel putative mechanisms to link circadian clocks to healthy aging.

J Neural Transm (Vienna). 2015 Aug;122 Suppl 1:S75-82. doi: 10.1007/s00702-013-1128-4. Epub 2013 Dec 3.

SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging.

Cell. 2013 Jun 20;153(7):1448-60. doi: 10.1016/j.cell.2013.05.027.

本文引用的文献

Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction.

J Clin Invest. 2011 Nov;121(11):4281-8. doi: 10.1172/JCI58554. Epub 2011 Oct 10.

Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction.

Cell. 2010 Nov 24;143(5):802-12. doi: 10.1016/j.cell.2010.10.002.

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney.

J Clin Invest. 2010 Apr;120(4):1043-55. doi: 10.1172/JCI41376. Epub 2010 Mar 24.

Sir2 links chromatin silencing, metabolism, and aging.

Genes Dev. 2000 May 1;14(9):1021-6.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

相似文献

Sirtuins and calorie restriction.

Nat Rev Mol Cell Biol. 2012 Feb 29;13(4):207. doi: 10.1038/nrm3308.

Utilizing calorie restriction to evaluate the role of sirtuins in healthspan and lifespan of mice.

Methods Mol Biol. 2013;1077:303-11. doi: 10.1007/978-1-62703-637-5_20.

Sirtuins as potential targets for metabolic syndrome.

Nature. 2006 Dec 14;444(7121):868-74. doi: 10.1038/nature05486.

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction.

Genes Dev. 2006 Nov 1;20(21):2913-21. doi: 10.1101/gad.1467506.

Sir2 mediates longevity in the fly through a pathway related to calorie restriction.

Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15998-6003. doi: 10.1073/pnas.0404184101. Epub 2004 Nov 1.

Increase in activity during calorie restriction requires Sirt1.

Science. 2005 Dec 9;310(5754):1641. doi: 10.1126/science.1118357.

At the crossroad of lifespan, calorie restriction, chromatin and disease: meeting on sirtuins.

Cell Cycle. 2010 May 15;9(10):1907-12. doi: 10.4161/cc.9.10.11481.

Calorie restriction--the SIR2 connection.

Cell. 2005 Feb 25;120(4):473-82. doi: 10.1016/j.cell.2005.01.029.

Sir2-independent life span extension by calorie restriction in yeast.

PLoS Biol. 2004 Sep;2(9):E296. doi: 10.1371/journal.pbio.0020296. Epub 2004 Aug 24.

Sir-2.1 modulates 'calorie-restriction-mediated' prevention of neurodegeneration in Caenorhabditis elegans: implications for Parkinson's disease.

Biochem Biophys Res Commun. 2011 Sep 23;413(2):306-10. doi: 10.1016/j.bbrc.2011.08.092. Epub 2011 Aug 26.

引用本文的文献

Mitochondrial sirtuin 4 shapes the intestinal microbiota of Drosophila by controlling lysozyme expression.

Anim Microbiome. 2025 Jun 13;7(1):63. doi: 10.1186/s42523-025-00431-x.

Inflammation and DNA damage: cause, effect or both.

Nat Rev Rheumatol. 2023 Apr;19(4):200-211. doi: 10.1038/s41584-022-00905-1. Epub 2023 Feb 7.

Chrononutrition-When We Eat Is of the Essence in Tackling Obesity.

Nutrients. 2022 Nov 29;14(23):5080. doi: 10.3390/nu14235080.

Yeast mismatch repair components are required for stable inheritance of gene silencing.

PLoS Genet. 2020 May 29;16(5):e1008798. doi: 10.1371/journal.pgen.1008798. eCollection 2020 May.

Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins.

J Biol Chem. 2016 Jul 8;291(28):14677-94. doi: 10.1074/jbc.M116.726307. Epub 2016 May 18.

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.

Nat Commun. 2015 Apr 14;6:6656. doi: 10.1038/ncomms7656.

SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence.

Aging Cell. 2014 Oct;13(5):890-9. doi: 10.1111/acel.12247. Epub 2014 Jul 18.

The controversial world of sirtuins.

Drug Discov Today Technol. 2014 Jun;12:e9-e17. doi: 10.1016/j.ddtec.2012.08.003.

Novel putative mechanisms to link circadian clocks to healthy aging.

J Neural Transm (Vienna). 2015 Aug;122 Suppl 1:S75-82. doi: 10.1007/s00702-013-1128-4. Epub 2013 Dec 3.

SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging.

Cell. 2013 Jun 20;153(7):1448-60. doi: 10.1016/j.cell.2013.05.027.

本文引用的文献

Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction.

J Clin Invest. 2011 Nov;121(11):4281-8. doi: 10.1172/JCI58554. Epub 2011 Oct 10.

Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction.

Cell. 2010 Nov 24;143(5):802-12. doi: 10.1016/j.cell.2010.10.002.

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney.

J Clin Invest. 2010 Apr;120(4):1043-55. doi: 10.1172/JCI41376. Epub 2010 Mar 24.

Sir2 links chromatin silencing, metabolism, and aging.

Genes Dev. 2000 May 1;14(9):1021-6.