Luo Xin-Feng, Lei Fan, He Yi, Pei Shu-Chen, Hai Li, Qian Shan, Wu Yong
Key Laboratory of Drug Targeting and Drug Delivery Systems of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.
J Asian Nat Prod Res. 2012;14(4):314-21. doi: 10.1080/10286020.2011.653348.
Pennogenin 3-O-β-D-glucopyranosyl-(1 → 3)-[α-L-rhamnopyranosyl-(1 → 2)]-β-D-glucopyranoside, a monodesmosidic saponin isolated from Paris polyphylla Smith var. yunnanensis with promised antitumor activities, was firstly synthesized from glucoside thiol via nine steps and with 27% overall yield.
重楼皂苷Ⅶ，一种从云南重楼中分离得到的具有抗肿瘤活性的单糖链皂苷，首次通过硫醇糖苷经九步反应合成，总收率为27%。
