Gao Liang, Zhang Lin, Wang Li-Ming, Liu Jiang-Yun, Cai Pei-Lie, Yang Shi-Lin
College of Pharmaceutical Science, Soochow University, Suzhou 215123, China.
J Asian Nat Prod Res. 2012;14(4):333-41. doi: 10.1080/10286020.2011.653685.
Phytochemical investigation of methanol extract from the whole plants of Patrinia scabiosifolia Fisch. resulted in the isolation of three new triterpenoid saponins (1-3) along with twelve known triterpenoids (4-15). The structures of the new compounds were established as 11α, 12α-epoxy-3-O-β-D-xylopyranosyl-olean-28, 13β-olide (1), 11α, 12α-epoxy-3-O-β-D-xylopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-β-D-xylopyranosyl-olean-28, 13β-olide (2), and 3-O-β-D-xylopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-β-D-xylopyranosyl oleanolic acid 28-O-β-D-glucopyranoside (3) on the basis of various spectroscopic analyses (including different 1D and 2D NMR spectroscopies and high-resolution electrospray ionization mass spectrometry) and chemical evidences.
对黄花败酱全草甲醇提取物进行植物化学研究，从中分离出3个新的三萜皂苷（1 - 3）以及12个已知的三萜类化合物（4 - 15）。基于各种光谱分析（包括不同的一维和二维核磁共振光谱以及高分辨率电喷雾电离质谱）和化学证据，确定新化合物的结构分别为11α, 12α - 环氧 - 3 - O - β - D - 吡喃木糖基 - 齐墩果 - 28, 13β - 内酯（1）、11α, 12α - 环氧 - 3 - O - β - D - 吡喃木糖基 - (1→3) - α - L - 吡喃鼠李糖基 - (1→2) - β - D - 吡喃木糖基 - 齐墩果 - 28, 13β - 内酯（2）和3 - O - β - D - 吡喃木糖基 - (1→3) - α - L - 吡喃鼠李糖基 - (1→2) - β - D - 吡喃木糖基齐墩果酸28 - O - β - D - 吡喃葡萄糖苷（3）。
