空心莲子草中的细胞毒性三萜皂苷。

Cytotoxic triterpene saponins from Alternanthera philoxeroides.

作者信息

Fang Jin-Bo, Yao Zhi, Chen Jia-Chun, Liu Yan-Wen, Takaishi Yoshihisa, Duan Hong-Quan

机构信息

School of Pharmaceutical Sciences, Research Center of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.

出版信息

J Asian Nat Prod Res. 2009;11(3):261-6. doi: 10.1080/10286020802684656.

DOI:10.1080/10286020802684656

PMID:19408151

Abstract

Four new pentacyclic triterpene saponins, philoxeroidesides A-D (1-4) were isolated from the aerial parts of Alternanthera philoxeroides. Their structures were elucidated on the basis of 1D- and 2D-NMR experiments and MS analyses. Philoxeroidesides A-D (1-4) showed cytotoxic activities against SK-N-SH and HL60 cell lines.

摘要

从空心莲子草地上部分分离得到4个新的五环三萜皂苷，即莲子草苷A-D（1-4）。通过一维和二维核磁共振实验以及质谱分析确定了它们的结构。莲子草苷A-D（1-4）对SK-N-SH和HL60细胞系显示出细胞毒活性。