Lahu Ali, Backa Teuta, Ismaili Jehona, Lahu Vendenis, Saiti Valton
Clinic of Rheumatology, University Clinical Center of Kosova, Prishtina, Kosova.
HUCT-Clinic of Rheumatology, Tirana, Albania.
Med Arch. 2015 Feb;69(1):42-5. doi: 10.5455/medarh.2015.69.42-45. Epub 2015 Feb 21.
Reactive arthritis is an autoimmune condition that occurs as a reaction against an infection site elsewhere in the body. Reactive arthritis affects mostly young ages, mainly group age 20-40 y.o., mostly males with ratio 2:1 against females, sometimes 3:1, and even 14:1. The purpose of the study was to observe the mode of illness presentation based on the number of affected joints.
During the 01.03.2012 - 01.03.2014 in the Clinic for Rheumatology and O.S.I.R. "Vendenisi - AL" in Besiana have been examined, elaborated and hospitalized 100 patients with reactive arthritis, out of them 66 males and 34 females. Patients underwent necessary laboratory, hematological, biochemical, and immunological examinations. Subsequently each affected joint has been examined based on the propedeutics rules (inspection, palpation and assessment of the level of motility), as well as x ray examination.
From 100 examined patients 66% were males and 34% females respectively. 11% of them were in the 10-20y.o. group age, 30% belonged to group age 21-30 y.o., 24% of patients to 31-40 y.o. group age, 30% to 41-50 y.o. group age, and 5% of patients to the group age over the 51 year old. Regarding the affected articulations and modes of illness presentation, we've obtained the following results: Knee was affected in 64.7% female and 52,12% male patients respectively, T/C joint in 50% female and 57.57% male patients, MTPH joint in 41.11% female and 48.48% male patients respectively, and R/C joint in 44.11% female and 48.48% male patients respectively. Oligoarticular type is seen in 73% male and 70% female patients. Monoarticular type is seen in 14% male and 13% female patients, and poliarticular type is seen in 10% male and 14% female patients respectively. Results from our study have revealed that: reactive arthritis is more frequent in males than females in ratio 2:1 in the infections of urogenital infection, 3:1 in nasopharyngeal infections, and similar in infections of enteral origin.
Reactive arthritis mostly attacks young ages 20-40 y.o., while over the age of 50 and below the age of 20 is rarely seen. First reactive arthritis attack in males occurs earlier than in females. Most affected joints are: knee, talocrural joint, metatarsophalangeal (MTPH) joint, radiocarpal (R/C) joint, and proximal interphalanteal (PIPH) joint. Oligoarticular mode of illness presentation is 2.5 more frequent than mono and poliarticular mode of illness presentation.
反应性关节炎是一种自身免疫性疾病，它是机体对身体其他部位感染灶产生反应而出现的病症。反应性关节炎主要影响年轻人，主要发病年龄在20 - 40岁，男性居多，男女比例为2:1，有时为3:1，甚至可达14:1。本研究的目的是根据受累关节的数量观察疾病的表现方式。
2012年3月1日至2014年3月1日期间，在贝西亚纳的风湿病与职业疾病临床中心“Vendenisi - AL”对100例反应性关节炎患者进行了检查、诊断并安排住院，其中男性66例，女性34例。患者接受了必要的实验室、血液学、生化及免疫学检查。随后，根据诊疗规范（视诊、触诊及活动度评估）对每个受累关节进行检查，并进行了X线检查。
在100例受检患者中，男性占66%，女性占34%。其中，11%的患者年龄在10 - 20岁，30%属于21 - 30岁年龄组，24%的患者年龄在31 - 40岁，30%在41 - 50岁，5%的患者年龄超过51岁。关于受累关节及疾病表现方式，我们得到了以下结果：膝关节受累的女性患者占64.7%，男性患者占52.12%；跗/踝关节受累的女性患者占50%，男性患者占57.57%；跖趾关节受累的女性患者占41.11%，男性患者占48.48%；桡腕关节受累的女性患者占44.11%，男性患者占48.48%。少关节型在男性患者中占73%，在女性患者中占70%。单关节型在男性患者中占14%，在女性患者中占13%；多关节型在男性患者中占10%，在女性患者中占14%。我们的研究结果表明：在泌尿生殖系统感染中，反应性关节炎男性发病率高于女性，比例为2:1；在鼻咽部感染中，比例为3:1；在肠道源性感染中，男女发病率相似。
反应性关节炎主要侵袭20 - 40岁的年轻人，50岁以上及20岁以下者少见。男性首次发生反应性关节炎的时间早于女性。最常受累的关节为：膝关节、距小腿关节、跖趾关节、桡腕关节及近端指间关节。少关节型疾病表现方式的发生率比单关节型和多关节型高2.5倍。
