School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, 510640, China.
Chem Commun (Camb). 2012 Apr 11;48(29):3545-7. doi: 10.1039/c2cc17717j. Epub 2012 Mar 1.
The palladium-catalyzed and CsF-promoted annulation reaction of bromoalkynes and isocyanides regioselectively affords a diverse set of 5-iminopyrrolone derivatives. This chemistry presumably proceeds through the bromoacrylamide intermediates, which can be readily prepared from the nucleophilic addition reaction of isocyanides to bromoalkynes in the presence of CsF.
钯催化和氟化铯促进的溴代炔烃和异氰化物的环化反应区域选择性地提供了一系列不同的 5-亚氨基吡咯烷酮衍生物。这种化学过程可能是通过溴丙烯酰胺中间体进行的，该中间体可以通过异氰化物在氟化铯存在下与溴代炔烃的亲核加成反应来容易地制备。
