Oztürk Metin İshak, Koca Orhan, Tüken Murat, Keleş Muzaffer Oğuz, Ilktaç Abdullah, Karaman M Ihsan
Department of Urology, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.
Urol Int. 2012;88(4):454-8. doi: 10.1159/000336137. Epub 2012 Feb 23.
Premature ejaculation (PE) is a frequently encountered sexual dysfunction in men. It significantly impairs quality of life of the affected male and his partner. The aim of this study is to investigate the role of hormonal factors in patients with PE.
107 male patients aged between 26 and 64 years (mean 45.1 ± 10.36) who consulted our outpatient clinics with complaints of PE and 94 healthy males (48.1 ± 11.81 years) as a control group were included in the study.
When mean serum hormone concentrations of both groups were compared, levels of prolactin and free T4 were found to be significantly higher in the PE group relative to the control group (p < 0.05). At least one of the hormonal parameters was abnormal in 36 cases (33.6%) with PE, compared to only 22 (23.4%) of the controls. The number of hyperprolactinemic cases was found to be significantly increased in the PE group (p < 0.05).
We feel that during the evaluation of this problem, which affects great numbers of men and their partners throughout the world, consideration of potential effects of hormonal factors might be beneficial.
早泄（PE）是男性中常见的性功能障碍。它严重损害了受影响男性及其伴侣的生活质量。本研究的目的是调查激素因素在早泄患者中的作用。
本研究纳入了107名年龄在26至64岁之间（平均45.1±10.36岁）因早泄前来门诊就诊的男性患者，以及94名健康男性（48.1±11.81岁）作为对照组。
比较两组的平均血清激素浓度时，发现早泄组的催乳素和游离甲状腺素水平显著高于对照组（p<0.05）。早泄患者中有36例（33.6%）至少有一项激素参数异常，而对照组中只有22例（23.4%）。发现早泄组高催乳素血症病例数显著增加（p<0.05）。
我们认为，在评估这个影响全球大量男性及其伴侣的问题时，考虑激素因素的潜在影响可能是有益的。
