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非内镜下、微创性颅骨穹窿重塑术治疗矢状缝早闭且术后无需佩戴头盔

Nonendoscopic, minimally invasive calvarial vault remodeling without postoperative helmeting for sagittal synostosis.

作者信息

Mutchnick Ian S, Maugans Todd A

机构信息

Division of Pediatric Neurosurgery, Kosair Children's Hospital, Norton Neuroscience Institute, Louisville, KY, USA.

出版信息

J Neurosurg Pediatr. 2012 Mar;9(3):222-7. doi: 10.3171/2011.12.PEDS11306.

DOI:10.3171/2011.12.PEDS11306
PMID:22380948
Abstract

OBJECT

Multiple surgical procedures have been described for the management of isolated nonsyndromic sagittal synostosis. Minimally invasive techniques have been recently emphasized, but these techniques necessitate the use of an endoscope and postoperative helmeting. The authors assert that a safe and effective, more "minimalistic" approach is possible, avoiding the use of endoscopic visualization and routine postoperative application of a cranial orthosis.

METHODS

A single-institution cohort analysis was performed on 18 cases involving infants treated for isolated nonsyndromic sagittal synostosis between 2008 and 2010 using a nonendoscopic, minimally invasive calvarial vault remodeling (CVR) procedure without postoperative helmeting. The surgical technique is described. Variables analyzed were: age at time of surgery, sex, estimated blood loss (EBL), operative time, intraoperative complications, postoperative complications, length of stay, pre- and postoperative cephalic index (CI), clinical impressions, and results of a 5-question nonstandardized questionnaire administered to patient caregivers regarding outcome.

RESULTS

Eleven male and 7 female infants (mean age 2.3 months) were included in the study. The mean duration of follow-up was 16.4 months (range 6-38 months). The mean procedural time was 111 minutes (range 44-161 minutes). The mean length of stay was 2.3 days (range 2-3 days). The mean EBL in all 18 patients was 101.4 ml (range 30-475 ml). One patient had significant bone bleeding resulting in an EBL of 475 ml. Excluding this patient, the mean EBL was 79.4 ml (range 30-150 ml). There were no deaths or intraoperative complications; one patient had a superficial wound infection. The mean CI was 69 preoperatively versus 79 postoperatively, a statistically significant difference (p < 0.0001). Two patients were offered helmeting for suboptimal surgical outcome; one family declined and the single helmeted patient showed improvement at 2 months. No patient has undergone further surgery for correction of primary deformity, secondary deformities, or bony irregularities. Complete questionnaire data were available for 14 (78%) of the 18 patients; 86% of the respondents were pleased with the cosmetic outcome, 92% were happy to have avoided helmeting, 72% were doubtful that helmeting would have provided more significant correction, and 86% were doubtful that further surgery would be necessary. Small, palpable, aesthetically insignificant skull irregularities were reported by family members in 6 cases (43%).

CONCLUSIONS

The authors present a nonendoscopic, minimally invasive CVR procedure without postoperative helmeting. Their small series demonstrates this to be a safe and efficacious procedure for isolated nonsyndromic sagittal synostosis, with improvements in CI at a mean follow-up of 16.1 months, commensurate with other techniques, and with overall high family satisfaction. Use of a CVR cranial orthosis in a delayed fashion can be effective for the infrequent patient in whom this approach results in suboptimal correction.

摘要

目的

已有多种手术方法用于治疗孤立性非综合征性矢状缝早闭。近年来,微创技术备受关注,但这些技术需要使用内窥镜和术后佩戴头盔。作者认为,有可能采用一种更“简约”的安全有效方法,避免使用内窥镜可视化和常规术后佩戴颅骨矫形器。

方法

对2008年至2010年间18例接受孤立性非综合征性矢状缝早闭治疗的婴儿进行单机构队列分析,采用非内窥镜微创颅骨穹窿重塑(CVR)手术,术后不佩戴头盔。描述了手术技术。分析的变量包括:手术时年龄、性别、估计失血量(EBL)、手术时间、术中并发症、术后并发症、住院时间、术前和术后头指数(CI)、临床印象,以及向患者护理人员发放的一份关于结果的5个问题的非标准化问卷的结果。

结果

该研究纳入了11名男婴和7名女婴(平均年龄2.3个月)。平均随访时间为16.4个月(范围6 - 38个月)。平均手术时间为111分钟(范围44 - 161分钟)。平均住院时间为2.3天(范围2 - 3天)。18例患者的平均EBL为101.4 ml(范围30 - 475 ml)。1例患者出现严重骨出血,EBL达至475 ml。排除该患者后,平均EBL为79.4 ml(范围30 - 150 ml)。无死亡病例或术中并发症;1例患者发生浅表伤口感染。术前平均CI为69,术后为79,差异有统计学意义(p < 0.0001)。2例患者因手术效果欠佳而接受头盔治疗;1个家庭拒绝,仅1例佩戴头盔的患者在2个月时有所改善。没有患者因原发性畸形、继发性畸形或骨质不规则而接受进一步手术矫正。18例患者中有14例(78%)可获得完整问卷数据;86%的受访者对美容效果满意,92%很高兴避免了佩戴头盔,72%怀疑佩戴头盔是否能提供更显著的矫正效果,86%怀疑是否需要进一步手术。6例(43%)家庭成员报告有小的、可触及的、美学上不显著的颅骨不规则情况。

结论

作者介绍了一种非内窥镜微创CVR手术,术后不佩戴头盔。他们的小样本系列研究表明,这是一种治疗孤立性非综合征性矢状缝早闭的安全有效方法,平均随访16.1个月时CI有所改善,与其他技术相当,且总体家庭满意度较高。对于这种方法矫正效果欠佳的少数患者,延迟使用CVR颅骨矫形器可能有效。

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